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    COVID-19 in children with haematological malignancies

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    Authors
    Millen, G. C.
    Arnold, R.
    Cazier, J. B.
    Curley, H.
    Feltbower, R.
    Gamble, A.
    Glaser, A.
    Grundy, R. G.
    Kirton, L.
    Lee, L. Y. W.
    McCabe, Martin G
    Palles, C.
    Phillips, B.
    Stiller, C. A.
    Varnai, C
    Kearns, P.
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    Affiliation
    Cancer Research UK Clinical Trials Unit, University of Birmingham Institute of Cancer and Genomic Sciences, Birmingham, UK
    Issue Date
    2021
    
    Metadata
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    Abstract
    Background: Children with cancer are not at increased risk of severe SARS-CoV-2 infection; however, adults with haematological malignancies have increased risk of severe infections compared with non-haematological malignancies. Methods: We compared patients with haematological and non-haematological malignancies enrolled in the UK Paediatric Coronavirus Cancer Monitoring Project between 12 March 2020 and 16 February 2021. Children who received stem cell transplantation were excluded. Results: Only 2/62 patients with haematological malignancy had severe/critical infections, with an OR of 0.5 for patients with haematological compared with non-haematological malignancies. Interpretation: Children with haematological malignancies are at no greater risk of severe SARS-CoV-2 infection than those with non-haematological malignancies.
    Citation
    Millen GC, Arnold R, Cazier J-B, Curley H, Feltbower R, Gamble A, et al. COVID-19 in children with haematological malignancies. Arch Dis Child. 2021 Jul 22;archdischild-2021-322062.
    Journal
    Archives of Disease in Childhood
    URI
    http://hdl.handle.net/10541/624497
    DOI
    10.1136/archdischild-2021-322062
    PubMed ID
    34301621
    Additional Links
    https://dx.doi.org/10.1136/archdischild-2021-322062
    Type
    Other
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1136/archdischild-2021-322062
    Scopus Count
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    All Paterson Institute for Cancer Research

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