• Login
    View Item 
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ChristieCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjects

    My Account

    LoginRegister

    Local Links

    The Christie WebsiteChristie Library and Knowledge Service

    Statistics

    Display statistics

    Clinical performance status and technical factors affecting outcomes from percutaneous transhepatic biliary interventions; a multicentre, prospective, observational cohort study.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    34254176.pdf
    Size:
    383.2Kb
    Format:
    PDF
    Description:
    From UNPAYWALL
    Download
    Authors
    Makris, G. C.
    Macdonald, A. C.
    Allouni, K.
    Corrigall, H.
    Tapping, C. R.
    Hughes, J. P.
    Anthony, S.
    Boardman, P.
    Patel, R.
    Wigham, A.
    Husainy, M. A.
    See, T. C.
    Cast, J.
    Olliff, S.
    Travis, S.
    Laasch, Hans-Ulrich
    Nice, C
    Uberoi, R.
    Show allShow less
    Affiliation
    Vascular and Interventional Radiology Department, Guy's and St Thomas' Hospital, NHS Foundation Trust, London.
    Issue Date
    2021
    
    Metadata
    Show full item record
    Abstract
    Purpose: The purpose of this study was to evaluate the predictive value of a 'Modified Karnofsky Scoring System' on outcomes and provide real-world data regarding the UK practice of biliary interventions. Materials and methods: A prospective multi-centred cohort study was performed. The pre-procedure modified Karnofsky score, the incidence of sepsis, complications, biochemical improvement and mortality were recorded out to 30 days post procedure. Results: A total of 292 patients (248 with malignant lesions) were suitable for inclusion in the study. The overall 7 and 30 day mortality was 3.1% and 16.1%, respectively. The 30 day sepsis rate was 10.3%. In the modified Karnofsky 'high risk' group the 7 day mortality was 9.7% versus 0% for the 'low risk' group (p = 0.002), whereas the 30 day mortality was 28.8% versus 13.3% (p = 0.003). The incidence of sepsis at 30 days was 19% in the high risk group versus 3.3% at the low risk group (p = 0.001) CONCLUSION: Percutaneous biliary interventions in the UK are safe and effective. Scoring systems such as the Karnofsky or the modified Karnofsky score hold promise in allowing us to identify high risk groups that will need more careful consideration and enhanced patient informed consent but further research with larger studies is warranted in order to identify their true impact on patient selection and outcomes post biliary interventions.
    Citation
    Makris GC, Macdonald AC, Allouni K, Corrigall H, Tapping CR, Hughes JP, et al. Clinical Performance Status and Technical Factors Affecting Outcomes from Percutaneous Transhepatic Biliary Interventions; A Multicentre, Prospective, Observational Cohort Study. Cardiovasc Intervent Radiol. 2021 Jul 12.
    Journal
    Cardiovascular and Interventional Radiology
    URI
    http://hdl.handle.net/10541/624442
    DOI
    10.1007/s00270-021-02888-0
    PubMed ID
    34254176
    Additional Links
    https://dx.doi.org/10.1007/s00270-021-02888-0
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1007/s00270-021-02888-0
    Scopus Count
    Collections
    All Christie Publications

    entitlement

    Related articles

    • Combined percutaneous-endoscopic stenting of malignant biliary obstruction: results from 106 consecutive procedures and identification of factors associated with adverse outcome.
    • Authors: Neal CP, Thomasset SC, Bools D, Sutton CD, Garcea G, Mann CD, Rees Y, Newland C, Robinson RJ, Dennison AR, Berry DP
    • Issue date: 2010 Feb
    • Palliation of Malignant Biliary Obstruction: Adverse Events are Common after Percutaneous Transhepatic Biliary Drainage.
    • Authors: Heedman PA, Åstradsson E, Blomquist K, Sjödahl R
    • Issue date: 2018 Mar
    • Survival benefit of percutaneous transhepatic biliary drainage for malignant biliary tract obstruction-a prospective study comparing external and internal drainage techniques.
    • Authors: Kumar S, Singh P, Kumar V, Kumar M, Mahto M
    • Issue date: 2021 Nov
    • Percutaneous transhepatic biliary stenting: the first experience and results of the Hospital of Kaunas University of Medicine.
    • Authors: Dambrauskas Z, Paskauskas S, Lizdenis P, Uktveris R, Pranculis A, Kaupas RS, Barauskas G, Pundzius J
    • Issue date: 2008
    • Comparison of percutaneous transhepatic biliary drainage and endoscopic biliary drainage in the management of malignant biliary tract obstruction: a meta-analysis.
    • Authors: Zhao XQ, Dong JH, Jiang K, Huang XQ, Zhang WZ
    • Issue date: 2015 Jan
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.