• Login
    View Item 
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ChristieCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjects

    My Account

    LoginRegister

    Local Links

    The Christie WebsiteChristie Library and Knowledge Service

    Statistics

    Display statistics

    Surgical treatment and outcomes of colorectal cancer patients during the COVID-19 pandemic: a national population-based study in England

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    34240077.pdf
    Size:
    510.5Kb
    Format:
    PDF
    Description:
    From UNPAYWALL
    Download
    Authors
    Kuryba, A.
    Boyle, J. M.
    Blake, H. A.
    Aggarwal, A.
    van der Meulen, J.
    Braun, Michael S
    Walker, K
    Fearnhead, N. S.
    Affiliation
    Clinical Effectiveness Unit, Royal College of Surgeons of England, London,
    Issue Date
    2021
    
    Metadata
    Show full item record
    Abstract
    To compare the management and outcomes of colorectal cancer (CRC) patients during the first 2 months of the COVID-19 pandemic with the preceding 6 months. Background: The pandemic has affected the diagnosis and treatment of CRC patients worldwide. Little is known about the safety of major resection and whether creating "cold" sites (COVID-free hospitals) is effective. Methods: A national study in England used administrative hospital data for 14,930 CRC patients undergoing surgery between October 1, 2019, and May 31, 2020. Mortality of CRC resection was compared before and after March 23, 2020 ("lockdown" start). Results: The number of elective CRC procedures dropped sharply during the pandemic (from average 386 to 214 per week), whereas emergency procedures were hardly affected (from 88 to 84 per week). There was little change in characteristics of surgical patients during the pandemic. Laparoscopic surgery decreased from 62.5% to 35.9% for elective and from 17.7% to 9.7% for emergency resections. Surgical mortality increased slightly (from 0.9% to 1.2%, P = 0.06) after elective and markedly (from 5.6% to 8.9%, P = 0.003) after emergency resections. The observed increase in mortality during the first phase of the pandemic was similar in "cold" and "hot" sites (P > 0.5 elective and emergency procedures). Conclusions: The pandemic resulted in a 50% reduction in elective CRC procedures during the initial surge and a substantial increase in mortality after emergency resection. There was no evidence that surgery in COVID-free "cold" sites led to better outcomes in the first 2 months.
    Citation
    Kuryba A, Boyle JM, Blake HA, Aggarwal A, van der Meulen J, Braun M, et al. Surgical Treatment and Outcomes of Colorectal Cancer Patients During the COVID-19 Pandemic: A National Population-based Study in England. Annals of Surgery Open. 2021 Jun;2(2):e071.
    Journal
    Annals of Surgery Open
    URI
    http://hdl.handle.net/10541/624438
    DOI
    10.1097/as9.0000000000000071
    PubMed ID
    34240077
    Additional Links
    https://dx.doi.org/10.1097/as9.0000000000000071
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1097/as9.0000000000000071
    Scopus Count
    Collections
    All Christie Publications

    entitlement

    Related articles

    • Oncologic long-term outcomes of emergency versus elective resection for colorectal cancer.
    • Authors: Lavanchy JL, Vaisnora L, Haltmeier T, Zlobec I, Brügger LE, Candinas D, Schnüriger B
    • Issue date: 2019 Dec
    • The impact of the first peak of the COVID-19 pandemic on colorectal cancer services in England and Wales: A national survey.
    • Authors: Boyle JM, Kuryba A, Blake HA, Aggarwal A, van der Meulen J, Walker K, Braun M, Fearnhead N
    • Issue date: 2021 Jul
    • Who requires emergency surgery for colorectal cancer and can national screening programmes reduce this need?
    • Authors: Askari A, Nachiappan S, Currie A, Bottle A, Abercrombie J, Athanasiou T, Faiz O
    • Issue date: 2017 Jun
    • Clinical presentation, management, screening and surveillance for colorectal cancer during the COVID-19 pandemic.
    • Authors: Akbulut S, Hargura AS, Garzali IU, Aloun A, Colak C
    • Issue date: 2022 Sep 16
    • Colorectal cancer care in the COVID-19 era: outcomes from a 'mixed site' model.
    • Authors: Ghosh S, Nevins EJ, Hicks GJ, Carney K, Emmett C, Mills SJ
    • Issue date: 2022 Apr
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.