• Login
    View Item 
    •   Home
    • The Manchester Institute Cancer Research UK
    • All Paterson Institute for Cancer Research
    • View Item
    •   Home
    • The Manchester Institute Cancer Research UK
    • All Paterson Institute for Cancer Research
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ChristieCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjectsProfilesView

    My Account

    LoginRegister

    Local Links

    The Christie WebsiteChristie Library and Knowledge Service

    Statistics

    Display statistics

    Patterns of practice for adaptive and real-time radiation therapy: part I intra-fraction motion

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Distefano, G.
    Bertholet, J.
    Poulsen, P.
    Roggen, T.
    Garibaldi, C.
    Tilly, N.
    Booth, J.
    Oelfke, U.
    Heijmen, B
    Aznar, Marianne Camille
    Affiliation
    St. Luke's Cancer Centre Royal Surrey County Hospital, Radiotherapy Physics, Guildford,
    Issue Date
    2020
    
    Metadata
    Show full item record
    Abstract
    Purpose or Objective The patterns of practice for adaptive and real-time radiation therapy (POP-ART RT) study aims to determine to which extent and how these methods are used in clinical practice and to understand the barriers to implementation. Here we report on part I: real-time respiratory motion management (RRMM). Material and Methods An institution-specific questionnaire developed during the 2nd ESTRO physics workshop was distributed worldwide. The focus was both on current practice and wishes for implementation. Therefore, centres not (yet) doing RRMM were encouraged to participate. RRMM was defined as the use of gating in free-breathing (FB) or breath-hold (BH), or tracking if the beam is continuously realigned with the target in real-time (via robotic or gimbal guidance, MLC or couch tracking). Respondents were asked if they used RRMM for selected tumor sites, the percentage of patients treated with RRMM, eligibility criteria and the monitoring signal used to guide gating or tracking. Respondents were also asked if they wished 1) to change or expand their use of RRMM for a tumor site already treated with RRMM and 2) to implement RRMM for a new tumor site and to rank the barriers to implementation in order of importance. Results The questionnaire was filled out by 200 centres from 41 countries. 68% of respondents used RRMM in at least one tumor site (“users”). Inspiration BH was the dominant technique for breast and lymphoma, whereas the spread in technique was greater for other sites (Table 1). Within any given tumor site, users only applied RRMM in a subset of patients. The most frequently selected percentage range of patients treated using RRMM was <25% for lung, pancreas and lymphoma, 25-50% for breast and >75% for liver. However, for liver and pancreas, >50% of users applied RRMM in >50% of patients. The main selection criteria was “left breast” (76%) for breast and SBRT (~50%) for lung, liver and pancreas. Across all tumor sites, external marker was the main RRMM signal used by >60% of respondents. For breast and lymphoma this was followed by surface imaging and breathing volume. KV/MV imaging was frequently used for liver and pancreas (with markers) and for lung (with or without markers) (Fig 1a). Tracking was mainly done on robotic linacs with hybrid monitoring. For breast and lung, 36% and 49% of the centres respectively wish to expand or implement RRMM (Fig 1b). In contrast, for liver and pancreas >55% of centres do not use RRMM and do not wish to implement it. Overall 71% of centres wish to implement RRMM for any new treatment site (Fig 1c) but human/financial resources and capacity on machine were the main barriers Conclusion Thirty-two percent of respondents do not use any form of RRMM. Although RRMM was common in the thorax, it was generally applied for less than half of the patients. There is an unmet need for RRMM solutions, particularly in lung cancer. The main barriers to implement RRMM are human/financial resources and capacity on the machine.
    Citation
    Distefano G, Bertholet J, Poulsen P, Roggen T, Garibaldi C, Tilly N, et al. OC-0703: Patterns of practice for adaptive and realtime radiation therapy: part I intra-fraction motion. Radiotherapy and Oncology . 2020 Nov;152:S394–5. 
    Journal
    Radiotherapy and Oncology
    URI
    http://hdl.handle.net/10541/624401
    Type
    Meetings and Proceedings
    Language
    en
    Collections
    All Paterson Institute for Cancer Research

    entitlement

     
    DSpace software (copyright © 2002 - 2025)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.