AffiliationDepartment of Research, Cancer Registry of Norway, PB 5313 Majorstuen, NO-0304 Oslo, Norway
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AbstractPatients' phenotypic characteristics might be associated with melanoma aggressiveness, but the evidence is scarce. This study examined the associations be-tween pigmentary characteristics, naevi and melanoma thickness. Data from the Norwegian Women and Cancer (NOWAC) study were analysed. By 2014, 1,243 women were diagnosed with a primary melanoma, and 1,140 had information on thickness. Using ordinal logistic regression models, the probability of being diagnosed with a specific thickness category was calculated by pigmentary score and naevi. Fair pigmentary score was associated with thinner trunk melanomas (probabilities of being diagnosed with a tumour ≤1.0 mm thickness were 74%, 66%, and 51% for fair, medium and dark pigmentary scores, respectively), but not the other sites. High number of naevi was associated with thicker nodular melanoma (NM) but not with super-ficial spreading melanoma. These findings suggest the need for greater overall vigilance and skin checks among women with fair pigmentary score. The association between naevi and NM suggest possible biological mechanisms.
CitationGhiasvand R, Green A, Sandanger T, Weiderpass E, Robsahm T, Veierød M. Phenotypic Characteristics and Melanoma Thickness in Women. Acta Derm Venereol . 2021;101(4):adv00446.
- [Family studies on the incidence of multiple pigmented naevi, familial skin melanoma and other malignant tumors].
- Authors: Szekeres L, Korom I
- Issue date: 1991 Sep 29
- [Nevus and malignant cutaneous melanoma].
- Authors: Morales Suárez-Varela MM, Llopis González A, Lacasaña Navarro M, Ferrándiz Ferragud J
- Issue date: 1991 May-Jun
- Distribution of congenital melanocytic naevi and congenital naevus-like naevi in a survey of 3406 Italian schoolchildren.
- Authors: Gallus S, Naldi L, Oncology Study Group of the Italian Group for Epidemiologic Research in Dermatology.
- Issue date: 2008 Aug
- [Risk factors for skin melanoma: genetic factors probably more important than exposure to sunlight].
- Authors: Pavel S, Smit NP
- Issue date: 2004 Nov 13
- [The prevalence of melanocytic naevi among teenagers].
- Authors: Csoma Z, Erdei Z, Bartusek D, Dósa-Rácz E, Dobozy A, Kemény L, Oláh J
- Issue date: 2008 Nov 16