Comparative performance of predictors of death from thin (≤1.0 mm) melanoma

Abstract

Despite overall favourable prognosis,1 thin (≤1.0 mm) cutaneous melanoma account for 23% of melanoma deaths in the high-risk general population of Queensland, Australia (2005-2009), because of the sheer volume of disease.2 The prospect of adjuvant systemic therapy has increased the focus on identifying patients with thin melanoma who are at high risk of death, such as through gene expression profiling (GEP), sentinel lymph node biopsy (SLNB), or prognostic models.3-5.