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    Consensus on the treatment and follow-up for metastatic castration-resistant prostate cancer: a report from the first global prostate cancer consensus conference for developing countries (PCCCDC)

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    Authors
    Maluf, F. C.
    Pereira, F. M. T.
    Silva, A. G.
    Dettino, A. L. A.
    Cardoso, A. P. G.
    Sasse, A. S.
    Soares, A.
    Kann, A. G.
    Herchenhorn, D.
    Jardim, D. L. F.
    Cortés, D. E. L.
    Kater, F. R.
    Morbeck, I. A. P.
    Reolon, J. F. N.
    Rinck, J. A., Jr.
    Zarbá, J. J.
    Sade, J. P.
    da Trindade, K. M.
    Costa, L.
    Dos Santos, L. V.
    Maia, M. C.
    Siqueira, M. B.
    Gillessen, Silke
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    Affiliation
    Hospital Israelita Albert Einstein, São Paulo, Brazil
    Issue Date
    2021
    
    Metadata
    Show full item record
    Abstract
    Purpose: To present a summary of the recommendations for the treatment and follow-up for metastatic castration-resistant prostate cancer (mCRPC) as acquired through a questionnaire administered to 99 physicians working in the field of prostate cancer in developing countries who attended the Prostate Cancer Consensus Conference for Developing Countries. Methods: A total of 106 questions out of more than 300 questions addressed the use of imaging in staging mCRPC, treatment recommendations across availability and response to prior drug treatments, appropriate drug treatments, and follow-up, and those same scenarios when limited resources needed to be considered. Responses were compiled and the percentages were presented by clinicians to support each response. Most questions had five to seven relevant options for response including abstain and/or unqualified to answer, or in the case of yes or no questions, the option to abstain was offered. Results: Most of the recommendations from this panel were in line with prior consensus, including the preference of a new antiandrogen for first-line therapy of mCRPC. Important aspects highlighted in the scenario of limited resources included the option of docetaxel as treatment preference as first-line treatment in several scenarios, docetaxel retreatment, consideration for reduced doses of abiraterone, and alternative schedules of an osteoclast-targeted therapy.
    Citation
    Maluf FC, Pereira FMT, Silva AG, Dettino ALA, Cardoso APG, Sasse AS, et al. Consensus on the Treatment and Follow-Up for Metastatic Castration-Resistant Prostate Cancer: A Report From the First Global Prostate Cancer Consensus Conference for Developing Countries (PCCCDC). JCO Global Oncology. 2021 Apr;(7):559–71.
    Journal
    JCO Global Oncology
    URI
    http://hdl.handle.net/10541/624050
    DOI
    10.1200/go.20.00511
    PubMed ID
    33856891
    Additional Links
    https://dx.doi.org/10.1200/go.20.00511
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1200/go.20.00511
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

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