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    Re-Irradiation of recurrent non-small cell lung icancer

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    Authors
    Hunter, B.
    Crockett, Cathryn
    Faivre-Finn, Corinne
    Hiley, C.
    Salem, Ahmed
    Affiliation
    The Royal Marsden Hospital, Chelsea, UK
    Issue Date
    2021
    
    Metadata
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    Abstract
    Locoregional recurrence occurs in 10%-30% of non-small cell lung cancer (NSCLC) after treatment with definitive (chemo)radiotherapy. Re-irradiation is the main curative-intent treatment option for these patients; however, it represents a therapeutic challenge for thoracic radiation oncologists. Re-irradiation practices are variable worldwide with lack of agreement on the optimal dose or the cumulative maximum dose acceptable for critical organs. The role of re-irradiation in NSCLC is also not clearly defined in the era of immunotherapy. In this review, we will present published and on-going re-irradiation studies for recurrent NSCLC. We will appraise available evidence for critical organ dose constraints and provide a framework for future therapeutic approaches and trials
    Citation
    Hunter B, Crockett C, Faivre-Finn C, Hiley C, Salem A. Re-Irradiation of Recurrent Non-Small Cell Lung Cancer. Semin Radiat Oncol. 2021;31(2):124-32.
    Journal
    Seminars in Radiation Oncology
    URI
    http://hdl.handle.net/10541/623837
    DOI
    10.1016/j.semradonc.2020.11.009
    PubMed ID
    33610269
    Additional Links
    https://dx.doi.org/10.1016/j.semradonc.2020.11.009
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.semradonc.2020.11.009
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