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dc.contributor.authorGreen, Adèle C
dc.contributor.authorPandeya, N.
dc.contributor.authorMorton, S.
dc.contributor.authorSimonidis, J.
dc.contributor.authorWhiteman, D. C.
dc.date.accessioned2021-01-25T01:13:49Z
dc.date.available2021-01-25T01:13:49Z
dc.date.issued2020en
dc.identifier.citationGreen AC, Pandeya N, Morton S, Simonidis J, Whiteman DC. Early detection of melanoma in specialised primary care practice in Australia. Cancer Epidemiol. 2021;70:101872.en
dc.identifier.pmid33360359en
dc.identifier.doi10.1016/j.canep.2020.101872en
dc.identifier.urihttp://hdl.handle.net/10541/623740
dc.description.abstractBackground: Primary care skin cancer clinics facilitate early treatment of melanoma in Australia. We investigated the clinical and histopathological features of melanomas diagnosed and treated in an established clinic in Brisbane. Methods: Retrospective audit of medical records of patients diagnosed with in situ or invasive primary cutaneous melanoma in a primary care clinic specializing in skin cancer, 2000-2017. Demographic and clinical data were standardly extracted by a medically-trained investigator. We used descriptive analyses to assess characteristics of patients and melanomas, and examine surgical management according to tumour thickness. Results: Of 380 patients (median age 57 years; 57 % male) newly diagnosed with 497 histologically-confirmed primary cutaneous melanomas, 369 were in situ and 128 invasive. Of the 369 in situ melanomas, 143 (39 %) were on the trunk and 87 (24 %) on the head and neck; 247 (67 %) were diagnosed by shave biopsy; and 141 (38 %) referred for wide local excision (WLE). Of the 128 invasive melanomas, only 21 (16 %) had thickness ≥ 0.8 mm and these occurred more often on head and neck than thin invasive melanomas (p = 0.02). The majority of invasive melanomas were diagnosed by excision biopsy, and WLE was carried out in a median of 3 days (melanomas ≥ 0.8 mm) and 2 days (<0.8 mm). The doctor detected the majority of in situ (83 %) and thin invasive (73 %) melanomas during surveillance, compared with 48 % of thicker invasive melanomas ≥ 0.8 mm (p < 0.001). Conclusion: In Australia, specialised primary care practice plays a major role in detection and treatment of early primary melanoma.en
dc.language.isoenen
dc.relation.urlhttps://dx.doi.org/10.1016/j.canep.2020.101872en
dc.titleEarly detection of melanoma in specialised primary care practice in Australiaen
dc.typeArticleen
dc.contributor.departmentPopulation Health Department, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Queensland, 4006, Australia; CRUK Manchester and Faculty of Biology, Medicine and Health, University of Manchester, Manchester,en
dc.identifier.journalCancer Epidemiologyen
dc.description.noteen]


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