Authors
Lagopati, N.Tsioli, P.
Mourkioti, I.
Polyzou, A.
Papaspyropoulos, A.
Zafiropoulos, A.
Evangelou, K.
Sourvinos, G.
Gorgoulis, Vassilis G
Affiliation
Molecular Carcinogenesis Group, Department of Histology and Embryology, School of Medicine, National Kapodistrian University of Athens (NKUA), Greece.Issue Date
2020
Metadata
Show full item recordAbstract
The worldwide COVID-19 pandemic outburst has caused a serious public health issue with increasing needs of accurate and rapid diagnostic and screening testing. This situation requires an optimized management of the chemical reagents, the consumables, and the human resources, in order to respond accurately and effectively, controlling the spread of the disease. Testing on pooled samples maximizes the number of tested samples, by minimizing the time and the lab supplies needed. The general conceptualization of the pooling method is based on mixing samples together in a batch. Individual testing is needed only if a specific pool exhibits a positive result. The development of alternative hybrid methods, based on "in house" protocols, utilizing commercially available consumables, in combination with a reliable pooling method would provide a solution, focusing on the better exploitation of the personnel and the lab supplies, allowing for rapid screening of a population in a reasonably short time.Citation
Lagopati N, Tsioli P, Mourkioti I, Polyzou A, Papaspyropoulos A, Zafiropoulos A, et al. Sample pooling strategies for SARS-CoV-2 detection. J Virol Methods. 2020;289:114044.Journal
Journal of Virological MethodsDOI
10.1016/j.jviromet.2020.114044PubMed ID
33316285Additional Links
https://dx.doi.org/10.1016/j.jviromet.2020.114044Type
ArticleLanguage
enae974a485f413a2113503eed53cd6c53
10.1016/j.jviromet.2020.114044
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