Bladder preservation: translating discovery for clinical impact in urothelial cancer
Affiliation
Department of Radiation Oncology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA.Issue Date
2020
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Show full item recordAbstract
Muscle-invasive bladder cancer can be treated with either radical cystectomy or bladder preservation approaches, and there is a need for reliable biomarkers to guide the optimal choice of therapy. The recent elucidation of the genomic landscape and biological drivers of bladder cancer has enabled the identification of tumor molecular features that may be helpful in driving clinical decision-making. Here, we summarize recent efforts to develop molecular biomarkers that could be leveraged to guide therapeutic decisions, post-treatment monitoring, and the optimal use of bladder preservation approaches for the effective treatment of muscle-invasive bladder cancer.Citation
Miyamoto DT, Abbosh PH, West CML, Mouw KW. Bladder preservation: Translating discovery for clinical impact in urothelial cancer. Urol Oncol. 2020.Journal
Urologic OncologyDOI
10.1016/j.urolonc.2020.11.021PubMed ID
33257220Additional Links
https://dx.doi.org/10.1016/j.urolonc.2020.11.021Type
ArticleLanguage
enae974a485f413a2113503eed53cd6c53
10.1016/j.urolonc.2020.11.021
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