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    Cardiac toxicity of thoracic radiotherapy: existing evidence and future directions

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    Authors
    Banfill, Kathryn
    Giuliani, M.
    Aznar, Marianne Camille
    Franks, K.
    McWilliam, Alan
    Schmitt, M.
    Sun, F.
    Vozenin, M. C.
    Faivre-Finn, Corinne
    Affiliation
    Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK
    Issue Date
    2020
    
    Metadata
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    Abstract
    The impact of radiotherapy on the heart has become an area of interest in recent years. Many different cardiac dose volume constraints have been associated with cardiac toxicity and survival however, no consistent constraint has been found. Many patients undergoing treatment for lung cancer have risk factors for cardiovascular disease or known cardiac comorbidities however, there is little evidence on the effects of radiotherapy on the heart in these patients. We aim to provide a summary of the existing literature on cardiac toxicity of lung cancer radiotherapy, propose strategies to avoid and manage cardiac toxicity and suggest avenues for future research.
    Citation
    Banfill K, Giuliani M, Aznar M, Franks K, McWilliam A, Schmitt M, et al. Cardiac Toxicity of Thoracic Radiotherapy: Existing Evidence and Future Directions. J Thorac Oncol. 2020.
    Journal
    Journal of Thoracic Oncology
    URI
    http://hdl.handle.net/10541/623663
    DOI
    10.1016/j.jtho.2020.11.002
    PubMed ID
    33278607
    Additional Links
    https://dx.doi.org/10.1016/j.jtho.2020.11.002
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.jtho.2020.11.002
    Scopus Count
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