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dc.contributor.authorValle, Juan W
dc.contributor.authorKelley, R. K.
dc.contributor.authorFuruse, J.
dc.contributor.authorEdeline, J.
dc.contributor.authorFinn, R. S.
dc.contributor.authorRen, Z.
dc.contributor.authorSu, S. C.
dc.contributor.authorMalhotra, U.
dc.contributor.authorSiegel, A. B.
dc.contributor.authorVogel, A.
dc.date.accessioned2020-12-08T05:36:26Z
dc.date.available2020-12-08T05:36:26Z
dc.date.issued2020en
dc.identifier.citationValle JW, Kelley RK, Furuse J, Edeline J, Finn RS, Ren Z, et al. 78TiP KEYNOTE-966 trial in progress: Pembrolizumab plus gemcitabine and cisplatin for advanced biliary tract cancer. Annals of Oncology. 2020;31:S270-S1.en
dc.identifier.doi10.1016/j.annonc.2020.08.056en
dc.identifier.urihttp://hdl.handle.net/10541/623461
dc.description.abstractBackground: Biliary tract cancer (BTC), comprising intra- and extra-hepatic cholangiocarcinoma and gallbladder cancer, is a rare and aggressive malignancy. Most patients (pts) present with advanced or unresectable disease, for which the current standard of care is gemcitabine plus cisplatin. Median survival for these pts is only 12 months, highlighting the need for more effective therapies. Pembrolizumab is a PD-1inhibitor that has demonstrated modest antitumor activity as monotherapy in pts with previously treated BTC and has improved survival when used in combination with platinum-based chemotherapy in other cancer types.en
dc.language.isoenen
dc.relation.urlhttps://dx.doi.org/10.1016/j.annonc.2020.08.056en
dc.titleKEYNOTE-966 trial in progress: Pembrolizumab plus gemcitabine and cisplatin for advanced biliary tract canceren
dc.typeMeetings and Proceedingsen
dc.contributor.departmentDivision of Cancer Sciences, University of Manchester/The Christie NHS Foundation Trust, Manchester, UK;en
dc.identifier.journalAnnals of Oncologyen
dc.description.noteen]
refterms.dateFOA2020-12-08T10:30:28Z


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