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dc.contributor.authorBarriuso, Jorge
dc.contributor.authorLamarca, Angela
dc.date.accessioned2020-10-06T13:33:49Z
dc.date.available2020-10-06T13:33:49Z
dc.date.issued2020en
dc.identifier.citationBarriuso J, Lamarca A. Clinical and Translational Research Challenges in Neuroendocrine Tumours. Curr Med Chem. 2020;27(29):4823-39.en
dc.identifier.pmid32031064en
dc.identifier.doi10.2174/0929867327666200207120725en
dc.identifier.urihttp://hdl.handle.net/10541/623350
dc.description.abstractNeuroendocrine tumours (NETs) represent a range of neoplasms that may arise from any (neuro)endocrine cell situated in any part of the human body. As any other rare diseases, NETs face several difficulties in relation to research. This review will describe some of the main challenges and proposed solutions faced by researchers with expertise in rare malignancies. Some of the most common challenges in clinical and translational research are enumerated in this review, covering aspects from clinical, translational and basic research. NETs being a heterogeneous group of diseases and a limited sample size of clinical and translational research projects are the main challenges. Challenges with NETs lay over the disparities between healthcare models to tackle rare diseases. NETs add an extra layer of complexity due to a numerous group of different entities. Prospective real-world data trials are an opportunity for rare cancers with the revolution of electronic health technologies. This review explores potential solutions to these challenges that could be useful not only to the NET community but also to other rare tumours researchers.en
dc.language.isoenen
dc.relation.urlhttps://dx.doi.org/10.2174/0929867327666200207120725en
dc.titleClinical and translational research challenges in neuroendocrine tumoursen
dc.typeArticleen
dc.contributor.departmentDivision of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.en
dc.identifier.journalCurrent Medicinal Chemistryen
dc.description.noteen]


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