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dc.contributor.authorGeorgiou, G.
dc.contributor.authorKumar, S.
dc.contributor.authorWurfel, J. U.
dc.contributor.authorUnderwood, Tracy
dc.contributor.authorThompson, J. M.
dc.contributor.authorHill, M. A.
dc.contributor.authorRowbottom, C. G.
dc.contributor.authorFenwick, J. D.
dc.date.accessioned2020-10-06T13:33:48Z
dc.date.available2020-10-06T13:33:48Z
dc.date.issued2020en
dc.identifier.citationGeorgiou G, Kumar S, Wurfel JU, Underwood TSA, Thompson JM, Hill MA, et al. Density compensated diodes for small field dosimetry: comprehensive testing and implications for design. Phys Med Biol. 2020;65(15):155011.en
dc.identifier.pmid32392539en
dc.identifier.doi10.1088/1361-6560/ab91d9en
dc.identifier.urihttp://hdl.handle.net/10541/623342
dc.description.abstractPurpose: In small megavoltage photon fields, the accuracies of an unmodified PTW 60017-type diode dosimeter and six diodes modified by adding airgaps of thickness 0.6-1.6 mm and diameter 3.6 mm have been comprehensively characterized experimentally and computationally. The optimally thick airgap for density compensation was determined, and detectors were micro-CT imaged to investigate differences between experimentally measured radiation responses and those predicted computationally. Methods: Detectors were tested onand off-axis, at 5 and 15 cm depths in 6 and 15 MV fields ≥ 0.5 × 0.5 cm2. Computational studies were carried out using the EGSnrc/BEAMnrc Monte Carlo radiation transport code. Experimentally, radiation was delivered using a Varian TrueBeam linac and doses absorbed by water were measured using Gafchromic EBT3 film and ionization chambers, and compared with diode readings. Detector response was characterized via the [Formula: see text] formalism, choosing a 4 × 4 cm2 reference field. Results: For the unmodified 60017 diode, the maximum error in small field doses obtained from diode readings uncorrected by [Formula: see text] factors was determined as 11.9% computationally at +0.25 mm off-axis and 5 cm depth in a 15 MV 0.5 × 0.5 cm2 field, and 11.7% experimentally at -0.30 mm off-axis and 5 cm depth in the same field. A detector modified to include a 1.6 mm thick airgap performed best, with maximum computationally and experimentally determined errors of 2.2% and 4.1%. The 1.6 mm airgap deepened the modified dosimeter's effective point of measurement by 0.5 mm. For some detectors significant differences existed between responses in small fields determined computationally and experimentally, micro-CT imaging indicating that these differences were due to within-tolerance variations in the thickness of an epoxy resin layer. Conclusions: The dosimetric performance of a 60017 diode detector was comprehensively improved throughout 6 and 15 MV small photon fields via density compensation. For this approach to work well with good detector-to-detector reproducibility, tolerances on dense component dimensions should be reduced to limit associated variations of response in small fields, or these components should be modified to have more water-like densities.en
dc.language.isoenen
dc.relation.urlhttps://dx.doi.org/10.1088/1361-6560/ab91d9en
dc.titleDensity compensated diodes for small field dosimetry: comprehensive testing and implications for designen
dc.typeArticleen
dc.contributor.departmentDepartment of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool,Liverpool L69 3BXen
dc.identifier.journalPhysics in Medicine and Biologyen
dc.description.noteen]
refterms.dateFOA2020-10-07T13:27:20Z


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