ESMO consensus conference recommendations on the management of metastatic melanoma: the ESMO Guidelines Committee
Authors
Keilholz, U.Ascierto, P. A.
Dummer, R.
Robert, C.
Lorigan, Paul C
van Akkooi, ACJ
Arance, A.
Blank, C. U.
Sileni, V. C.
Donia, M.
Faries, M. B.
Gaudy-Marqueste, C.
Gogas, H.
Grob, J. J.
Guckenberger, M.
Haanen, J.
Hayes, A. J.
Hoeller, C.
Lebb�, C.
Lugowska, I.
Mandal�, M.
Marquez-Rodas, I
Nathan, P.
Neyns, B.
Bagge, R. O.
Puig, S.
Rutkowski, P.
Schilling, B.
Sondak, V. K.
Tawbi, H.
Testori, A.
Michielin, O.
Affiliation
Charit� Comprehensive Cancer Center, Charit�-Universit�tsmedizin Berlin, Berlin, GermanyIssue Date
2020
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The European Society for Medical Oncology (ESMO) held a consensus conference on melanoma on 5-7 September 2019 in Amsterdam, The Netherlands. The conference included a multidisciplinary panel of 32 leading experts in the management of melanoma. The aim of the conference was to develop recommendations on topics that are not covered in detail in the current ESMO Clinical Practice Guideline and where available evidence is either limited or conflicting. The main topics identified for discussion were (i) the management of locoregional disease; (ii) targeted versus immunotherapies in the adjuvant setting; (iii) targeted versus immunotherapies for the first-line treatment of metastatic melanoma; (iv) when to stop immunotherapy or targeted therapy in the metastatic setting; and (v) systemic versus local treatment for brain metastases. The expert panel was divided into five working groups to each address questions relating to one of the five topics outlined above. Relevant scientific literature was reviewed in advance. Recommendations were developed by the working groups and then presented to the entire panel for further discussion and amendment before voting. This manuscript presents the results relating to the management of metastatic melanoma, including findings from the expert panel discussions, consensus recommendations and a summary of evidence supporting each recommendation. All participants approved the final manuscript.Citation
Keilholz U, Ascierto PA, Dummer R, Robert C, Lorigan P, van Akkooi A, et al. ESMO consensus conference recommendations on the management of metastatic melanoma: under the auspices of the ESMO Guidelines Committee. Annals of Oncology. 2020.Journal
Annals of OncologyDOI
10.1016/j.annonc.2020.07.004PubMed ID
32763453Additional Links
https://dx.doi.org/10.1016/j.annonc.2020.07.004Type
ArticleLanguage
enae974a485f413a2113503eed53cd6c53
10.1016/j.annonc.2020.07.004
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