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    Optimizing MR-guided radiotherapy for breast cancer patients

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    Authors
    Groot Koerkamp, M. L.
    Vasmel, J. E.
    Russell, N. S.
    Shaitelman, S. F.
    Anandadas, Carmel N
    Currey, A.
    Vesprini, D.
    Keller, B. M.
    De-Colle, C.
    Han, K.
    Braunstein, L. Z.
    Mahmood, F.
    Lorenzen, E. L.
    Philippens, M. E. P.
    Verkooijen, H. M.
    Lagendijk, J. J. W.
    Houweling, A. C.
    van den Bongard, H.
    Kirby, A. M.
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    Affiliation
    Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, Netherlands.
    Issue Date
    2020
    
    Metadata
    Show full item record
    Abstract
    Current research in radiotherapy (RT) for breast cancer is evaluating neoadjuvant as opposed to adjuvant partial breast irradiation (PBI) with the aim of reducing the volume of breast tissue irradiated and therefore the risk of late treatment-related toxicity. The development of magnetic resonance (MR)-guided RT, including dedicated MR-guided RT systems [hybrid machines combining an MR scanner with a linear accelerator (MR-linac) or 60Co sources], could potentially reduce the irradiated volume even further by improving tumour visibility before and during each RT treatment. In this position paper, we discuss MR guidance in relation to each step of the breast RT planning and treatment pathway, focusing on the application of MR-guided RT to neoadjuvant PBI.
    Citation
    Groot Koerkamp ML, Vasmel JE, Russell NS, Shaitelman SF, Anandadas CN, Currey A, et al. Optimizing MR-Guided Radiotherapy for Breast Cancer Patients. Frontiers in Oncology. 2020;10:1107.
    Journal
    Frontiers in Oncology
    URI
    http://hdl.handle.net/10541/623247
    DOI
    10.3389/fonc.2020.01107
    PubMed ID
    32850318
    Additional Links
    https://dx.doi.org/10.3389/fonc.2020.01107
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.3389/fonc.2020.01107
    Scopus Count
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