Celis, J. E.
Aaronson, N. K.
Adami, H. O.
de Lorenzo, F.
AffiliationThe Netherlands Cancer Institute, Amsterdam, the Netherlands.
MetadataShow full item record
AbstractA comprehensive translational cancer research approach focused on personalized and precision medicine, and covering the entire cancer research-care-prevention continuum has the potential to achieve in 2030 a 10-year cancer-specific survival for 75% of patients diagnosed in European Union (EU) member states with a well-developed healthcare system. Concerted actions across this continuum that spans from basic and preclinical research through clinical and prevention research to outcomes research, along with the establishment of interconnected high-quality infrastructures for translational research, clinical and prevention trials and outcomes research, will ensure that science-driven and social innovations benefit patients and individuals at risk across the EU. European infrastructures involving comprehensive cancer centres (CCCs) and CCC-like entities will provide researchers with access to the required critical mass of patients, biological materials and technological resources and can bridge research with healthcare systems. Here, we prioritize research areas to ensure a balanced research portfolio and provide recommendations for achieving key targets. Meeting these targets will require harmonization of EU and national priorities and policies, improved research coordination at the national, regional and EU level and increasingly efficient and flexible funding mechanisms. Long-term support by the EU and commitment of Member States to specialized schemes are also needed for the establishment and sustainability of trans-border infrastructures and networks. In addition to effectively engaging policymakers, all relevant stakeholders within the entire continuum should consensually inform policy through evidence-based advice.
CitationBerns A, Ringborg U, Celis JE, Heitor M, Aaronson NK, Abou?Zeid N, et al. Towards a cancer mission in Horizon Europe: recommendations. Molecular Oncology. 2020;14(8):1589-615.
- European Academy of Cancer Sciences - position paper.
- Authors: Adami HO, Berns A, Celis JE, de Vries E, Eggermont A, Harris A, Zur Hausen H, Pelicci PG, Ringborg U
- Issue date: 2018 Nov
- Towards a mission-oriented approach to cancer in Europe: an unmet need in cancer research policy.
- Authors: Celis JE, Heitor M
- Issue date: 2019 Mar
- The Porto European Cancer Research Summit 2021.
- Authors: Ringborg U, Berns A, Celis JE, Heitor M, Tabernero J, Schüz J, Baumann M, Henrique R, Aapro M, Basu P, Beets-Tan R, Besse B, Cardoso F, Carneiro F, van den Eede G, Eggermont A, Fröhling S, Galbraith S, Garralda E, Hanahan D, Hofmarcher T, Jönsson B, Kallioniemi O, Kásler M, Kondorosi E, Korbel J, Lacombe D, Carlos Machado J, Martin-Moreno JM, Meunier F, Nagy P, Nuciforo P, Oberst S, Oliveiera J, Papatriantafyllou M, Ricciardi W, Roediger A, Ryll B, Schilsky R, Scocca G, Seruca R, Soares M, Steindorf K, Valentini V, Voest E, Weiderpass E, Wilking N, Wren A, Zitvogel L
- Issue date: 2021 Sep 13
- Cancer Core Europe: A translational research infrastructure for a European mission on cancer.
- Authors: Eggermont AMM, Apolone G, Baumann M, Caldas C, Celis JE, de Lorenzo F, Ernberg I, Ringborg U, Rowell J, Tabernero J, Voest E, Calvo F
- Issue date: 2019 Mar
- The future of Cochrane Neonatal.
- Authors: Soll RF, Ovelman C, McGuire W
- Issue date: 2020 Nov