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    Towards a cancer mission in Horizon Europe: recommendations

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    Authors
    Berns, A.
    Ringborg, U.
    Celis, J. E.
    Heitor, M.
    Aaronson, N. K.
    Abou-Zeid, N.
    Adami, H. O.
    Apostolidis, K.
    Baumann, M.
    Bardelli, A.
    Bernards, R.
    Brandberg, Y.
    Caldas, C.
    Calvo, F.
    Dive, Caroline
    Eggert, A.
    Eggermont, A.
    Espina, C.
    Falkenburg, F.
    Foucaud, J.
    Hanahan, D.
    Helbig, U.
    J�nsson, B.
    Kalager, M.
    Karjalainen, S.
    K�sler, M.
    Kearns, P.
    K�rre, K.
    Lacombe, D.
    de Lorenzo, F.
    Meunier, F.
    Nettekoven, G.
    Oberst, S.
    Nagy, P.
    Philip, T.
    Price, R.
    Sch�z, J.
    Solary, E.
    Strang, P.
    Tabernero, J.
    Voest, E.
    Show allShow less
    Affiliation
    The Netherlands Cancer Institute, Amsterdam, the Netherlands.
    Issue Date
    2020
    
    Metadata
    Show full item record
    Abstract
    A comprehensive translational cancer research approach focused on personalized and precision medicine, and covering the entire cancer research-care-prevention continuum has the potential to achieve in 2030 a 10-year cancer-specific survival for 75% of patients diagnosed in European Union (EU) member states with a well-developed healthcare system. Concerted actions across this continuum that spans from basic and preclinical research through clinical and prevention research to outcomes research, along with the establishment of interconnected high-quality infrastructures for translational research, clinical and prevention trials and outcomes research, will ensure that science-driven and social innovations benefit patients and individuals at risk across the EU. European infrastructures involving comprehensive cancer centres (CCCs) and CCC-like entities will provide researchers with access to the required critical mass of patients, biological materials and technological resources and can bridge research with healthcare systems. Here, we prioritize research areas to ensure a balanced research portfolio and provide recommendations for achieving key targets. Meeting these targets will require harmonization of EU and national priorities and policies, improved research coordination at the national, regional and EU level and increasingly efficient and flexible funding mechanisms. Long-term support by the EU and commitment of Member States to specialized schemes are also needed for the establishment and sustainability of trans-border infrastructures and networks. In addition to effectively engaging policymakers, all relevant stakeholders within the entire continuum should consensually inform policy through evidence-based advice.
    Citation
    Berns A, Ringborg U, Celis JE, Heitor M, Aaronson NK, Abou?Zeid N, et al. Towards a cancer mission in Horizon Europe: recommendations. Molecular Oncology. 2020;14(8):1589-615.
    Journal
    Molecular Oncology
    URI
    http://hdl.handle.net/10541/623227
    DOI
    10.1002/1878-0261.12763
    PubMed ID
    32749074
    Additional Links
    https://dx.doi.org/10.1002/1878-0261.12763
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1002/1878-0261.12763
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

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