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    Considerations for the treatment of pancreatic cancer during the COVID-19 pandemic: the UK consensus position

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    Authors
    Jones, C. M.
    Radhakrishna, Ganesh
    Aitken, K.
    Bridgewater, J.
    Corrie, P.
    Eatock, M.
    Goody, R.
    Ghaneh, P.
    Good, J.
    Grose, D.
    Holyoake, D.
    Hunt, A.
    Jamieson, N. B.
    Palmer, D. H.
    Soonawalla, Z.
    Valle, Juan W
    Hawkins, M. A.
    Mukherjee, S.
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    Affiliation
    Faculty of Biological Sciences, University of Leeds, Leeds,
    Issue Date
    2020
    
    Metadata
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    Abstract
    The coronavirus disease 2019 (COVID-19) pandemic epicentre has moved to the USA and Europe, where it is placing unprecedented demands on healthcare resources and staff availability. These service constraints, coupled with concerns relating to an increased incidence and severity of COVID-19 among patients with cancer, should lead to re-consideration of the risk-benefit balance for standard treatment pathways. This is of particular importance to pancreatic cancer, given that standard diagnostic modalities such as endoscopy may be restricted, and that disease biology precludes significant delays in treatment. In light of this, we sought consensus from UK clinicians with an interest in pancreatic cancer for management approaches that would minimise patient risk and accommodate for healthcare service restrictions. The outcomes are described here and include recommendations for treatment prioritisation, strategies to bridge to later surgical resection in resectable disease and factors that modify the risk-benefit balance for treatment in the resectable through to the metastatic settings. Priority is given to strategies that limit hospital visits, including through the use of hypofractionated precision radiotherapy and chemoradiotherapy treatment approaches.
    Citation
    Jones CM, Radhakrishna G, Aitken K, Bridgewater J, Corrie P, Eatock M, et al. Considerations for the treatment of pancreatic cancer during the COVID-19 pandemic: the UK consensus position. Br J Cancer. 2020:1-5.
    Journal
    British Journal of Cancer
    URI
    http://hdl.handle.net/10541/623175
    DOI
    10.1038/s41416-020-0980-x
    PubMed ID
    32641867
    Additional Links
    https://dx.doi.org/10.1038/s41416-020-0980-x
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1038/s41416-020-0980-x
    Scopus Count
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