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dc.contributor.authorKhorana, A. A.
dc.contributor.authorMcNamara, Mairead G
dc.contributor.authorKakkar, A. K.
dc.contributor.authorStreiff, M. B.
dc.contributor.authorRiess, H.
dc.contributor.authorVijapurkar, U.
dc.contributor.authorKaul, S.
dc.contributor.authorWildgoose, P.
dc.contributor.authorSoff, G. A.
dc.date.accessioned2020-06-16T11:03:15Z
dc.date.available2020-06-16T11:03:15Z
dc.date.issued2020en
dc.identifier.citationA. A. Khorana, M. G. McNamara, A. K. Kakkar et al. Assessing Full Benefit of Rivaroxaban Prophylaxis in High-Risk Ambulatory Patients with Cancer: Thromboembolic Events in the Randomized CASSINI Trial. TH Open. 2020;4(2):e107-e112.en
dc.identifier.pmid32462111en
dc.identifier.doi10.1055/s-0040-1712143en
dc.identifier.urihttp://hdl.handle.net/10541/623029
dc.description.abstractIntroduction In the CASSINI study, rivaroxaban thromboprophylaxis significantly reduced primary venous thromboembolism (VTE) endpoints during the intervention period, but several thromboembolic events designated as secondary efficacy endpoints were not included in the primary analysis. This study was aimed to evaluate the full impact of rivaroxaban thromboprophylaxis on all prespecified thromboembolic endpoints occurring on study. Methods CASSINI was a double-blind, randomized, placebo-controlled study in adult ambulatory patients with cancer at risk for VTE (Khorana score /=2). Patients were screened at baseline for deep-vein thrombosis (DVT) and randomized if none was found. The primary efficacy endpoint was a composite of lower extremity proximal DVTen
dc.language.isoenen
dc.relation.urlhttps://dx.doi.org/10.1055/s-0040-1712143en
dc.titleAssessing full benefit of rivaroxaban prophylaxis in high-risk ambulatory patients with cancer: thromboembolic events in the randomized CASSINI Trialen
dc.typeArticleen
dc.contributor.departmentDepartment of Hematology and Medical Oncology, Cleveland Clinic, Cleveland, Ohio,en
dc.identifier.journalTH Openen
dc.description.noteen]
refterms.dateFOA2020-06-16T13:44:23Z


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