Show simple item record

dc.contributor.authorFornacon-Wood, Isabella
dc.contributor.authorMistry, Hitesh
dc.contributor.authorAckermann, Christoph J
dc.contributor.authorBlackhall, Fiona H
dc.contributor.authorMcPartlin, Andrew J
dc.contributor.authorFaivre-Finn, Corinne
dc.contributor.authorPrice, Gareth J
dc.contributor.authorO'Connor, James P B
dc.date.accessioned2020-06-16T11:03:10Z
dc.date.available2020-06-16T11:03:10Z
dc.date.issued2020en
dc.identifier.citationI. Fornacon-Wood, H. Mistry, C. J. Ackermann et al Reliability and prognostic value of radiomic features are highly dependent on choice of feature extraction platform. Eur Radiol. 2020.en
dc.identifier.pmid32483644en
dc.identifier.doi10.1007/s00330-020-06957-9en
dc.identifier.urihttp://hdl.handle.net/10541/623009
dc.description.abstractOBJECTIVE: To investigate the effects of Image Biomarker Standardisation Initiative (IBSI) compliance, harmonisation of calculation settings and platform version on the statistical reliability of radiomic features and their corresponding ability to predict clinical outcome. METHODS: The statistical reliability of radiomic features was assessed retrospectively in three clinical datasets (patient numbers: 108 head and neck cancer, 37 small-cell lung cancer, 47 non-small-cell lung cancer). Features were calculated using four platforms (PyRadiomics, LIFEx, CERR and IBEX). PyRadiomics, LIFEx and CERR are IBSI-compliant, whereas IBEX is not. The effects of IBSI compliance, user-defined calculation settings and platform version were assessed by calculating intraclass correlation coefficients and confidence intervals. The influence of platform choice on the relationship between radiomic biomarkers and survival was evaluated using univariable cox regression in the largest dataset. RESULTS: The reliability of radiomic features calculated by the different software platforms was only excellent (ICC 0.9) for 4/17 radiomic features when comparing all four platforms. Reliability improved to ICC " 0.9 for 15/17 radiomic features when analysis was restricted to the three IBSI-compliant platforms. Failure to harmonise calculation settings resulted in poor reliabilityen
dc.language.isoenen
dc.relation.urlhttps://dx.doi.org/10.1007/s00330-020-06957-9en
dc.titleReliability and prognostic value of radiomic features are highly dependent on choice of feature extraction platformen
dc.typeArticleen
dc.contributor.departmentDivision of Cancer Sciences, University of Manchester, Manchester, UK.en
dc.identifier.journalEuropean Radiologyen
dc.description.noteen]
refterms.dateFOA2020-06-16T14:35:51Z


Files in this item

Thumbnail
Name:
32483644.pdf
Size:
2.483Mb
Format:
PDF
Description:
From UNPAYWALL

This item appears in the following Collection(s)

Show simple item record