A CINful way to overcome addiction: how chromosomal instability enables cancer to overcome its oncogene addiction
AffiliationGenetics Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.
MetadataShow full item record
CitationBultitude WP, Schellekens J, Szydlo RM, Anthias C, Cooley SA, Miller JS, et al. Presence of donor-encoded centromeric KIR B content increases the risk of infectious mortality in recipients of myeloablative, T-cell deplete, HLA-matched HCT to treat AML. Bone Marrow Transplant. 2020.
JournalEmbo Molecular Medicine
- Targeting the CINful genome: Strategies to overcome tumor heterogeneity.
- Authors: Cunningham CE, MacAuley MJ, Yadav G, Vizeacoumar FS, Freywald A, Vizeacoumar FJ
- Issue date: 2019 Oct
- Oncogene addiction: pathways of therapeutic response, resistance, and road maps toward a cure.
- Authors: Pagliarini R, Shao W, Sellers WR
- Issue date: 2015 Mar
- Heat-shock protein 27 (HSP27, HSPB1) is synthetic lethal to cells with oncogenic activation of MET, EGFR and BRAF.
- Authors: Konda JD, Olivero M, Musiani D, Lamba S, Di Renzo MF
- Issue date: 2017 Jun
- Oncogene addiction as a foundation of targeted cancer therapy: The paradigm of the MET receptor tyrosine kinase.
- Authors: Orlando E, Aebersold DM, Medová M, Zimmer Y
- Issue date: 2019 Feb 28
- APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability.
- Authors: Sansregret L, Patterson JO, Dewhurst S, López-García C, Koch A, McGranahan N, Chao WCH, Barry DJ, Rowan A, Instrell R, Horswell S, Way M, Howell M, Singleton MR, Medema RH, Nurse P, Petronczki M, Swanton C
- Issue date: 2017 Feb