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dc.contributor.authorYoulden, DR
dc.contributor.authorBaade, PD
dc.contributor.authorGreen, Adèle C
dc.contributor.authorValery, PC
dc.contributor.authorMoore, AS
dc.contributor.authorAitken, JF
dc.date.accessioned2020-01-29T15:18:00Z
dc.date.available2020-01-29T15:18:00Z
dc.date.issued2019en
dc.identifier.citationYoulden DR, Baade PD, Green AC, Valery PC, Moore AS, Aitken JF. The incidence of childhood cancer in Australia, 1983-2015, and projections to 2035. Med J Aust. 2019.en
dc.identifier.pmid31876953en
dc.identifier.doi10.5694/mja2.50456en
dc.identifier.urihttp://hdl.handle.net/10541/622734
dc.description.abstractOBJECTIVES: To describe changes in childhood cancer incidence in Australia, 1983-2015, and to estimate projected incidence to 2035. DESIGN, SETTING: Population-based study; analysis of Australian Childhood Cancer Registry data for the 20 547 children under 15 years of age diagnosed with cancer in Australia between 1983 and 2015. MAIN OUTCOME MEASURES: Incidence rate changes during 1983-2015 were assessed by joinpoint regression, with rates age-standardised to the 2001 Australian standard population. Incidence projections to 2035 were estimated by age-period-cohort modelling. RESULTS: The overall age-standardised incidence rate of childhood cancer increased by 34% between 1983 and 2015, increasing by 1.2% (95% CI, +0.5% to +1.9%) per annum between 2005 and 2015. During 2011-2015, the mean annual number of children diagnosed with cancer in Australia was 770, an incidence rate of 174 cases (95% CI, 169-180 cases) per million children per year. The incidence of hepatoblastoma (annual percentage change [APC], +2.3%; 95% CI, +0.8% to +3.8%), Burkitt lymphoma (APC, +1.6%; 95% CI, +0.4% to +2.8%), osteosarcoma (APC, +1.1%; 95%, +0.0% to +2.3%), intracranial and intraspinal embryonal tumours (APC, +0.9%; 95% CI, +0.4% to +1.5%), and lymphoid leukaemia (APC, +0.5%; 95% CI, +0.2% to +0.8%) increased significantly across the period 1983-2015. The incidence rate of childhood melanoma fell sharply between 1996 and 2015 (APC, -7.7%; 95% CI, -10% to -4.8%). The overall annual cancer incidence rate is conservatively projected to rise to about 186 cases (95% CI, 175-197 cases) per million children by 2035 (1060 cases per year). CONCLUSIONS: The incidence rates of several childhood cancer types steadily increased during 1983-2015. Although the reasons for these rises are largely unknown, our findings provide a foundation for health service planning for meeting the needs of children who will be diagnosed with cancer until 2035.en
dc.language.isoenen
dc.relation.urlhttps://dx.doi.org/10.5694/mja2.50456en
dc.titleThe incidence of childhood cancer in Australia, 1983-2015, and projections to 2035en
dc.typeArticleen
dc.contributor.departmentCancer Council Queensland, Brisbane, QLDen
dc.identifier.journalMedical Journal of Australiaen
dc.description.noteen]
refterms.dateFOA2020-02-04T08:59:53Z


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