The role of postoperative thoracic radiotherapy and prophylactic cranial irradiation in early stage small cell lung cancer: Patient selection among ESTRO experts
Authors
Putora, PMDe, RD
Glatzer, M
Widder, J
Van, HP
Troost, EGC
Slotman, BJ
Ramella, S
Pottgen, C
Peeters, S
Nestle, U
McDonald, F
Le, PC
Dziadziuszko, R
Belderbos, J
Faivre-Finn, Corinne
Affiliation
Department of Radiation Oncology, Kantonsspital St. Gallen, Switzerland;Issue Date
2019
Metadata
Show full item recordAbstract
BACKGROUND: The role of prophylactic cranial irradiation (PCI) and thoracic radiotherapy (TRT) is unclear in resected small cell lung cancer (SCLC). METHODS: Thirteen European radiotherapy experts on SCLC were asked to describe their strategies on PCI and TRT for patients with resected SCLC. The treatment strategies were converted into decision trees and analyzed for consensus and discrepancies. RESULTS: For patients with resected SCLC and positive lymph nodes most experts recommend prophylactic cranial irradiation and thoracic radiotherapy. For elderly patients with resected node negative SCLC, most experts do not recommend thoracic radiotherapy or prophylactic cranial irradiation. CONCLUSION: PCI and TRT are considered in patients with resected SCLC and these treatments should be discussed with the patient in the context of shared decision-making.Citation
Putora PM, De Ruysscher D, Glatzer M, Widder J, Van Houtte P, Troost EGC, et al. The role of postoperative thoracic radiotherapy and prophylactic cranial irradiation in early stage small cell lung cancer: Patient selection among ESTRO experts. Radiother Oncol. 2019;145:45-8.Journal
Radiotherapy and OncologyDOI
10.1016/j.radonc.2019.11.022PubMed ID
31887577Additional Links
https://dx.doi.org/10.1016/j.radonc.2019.11.022Type
ArticleLanguage
enae974a485f413a2113503eed53cd6c53
10.1016/j.radonc.2019.11.022
Scopus Count
Collections
Related articles
- Prophylactic cranial irradiation in stage IV small cell lung cancer: Selection of patients amongst European IASLC and ESTRO experts.
- Authors: Putora PM, Glatzer M, Belderbos J, Besse B, Blackhall F, Califano R, Cappuzzo F, de Marinis F, Dziadziuszko R, Felip E, Faivre-Finn C, Früh M, Garrido P, Le Pechoux C, McDonald F, Nestle U, Novello S, O'Brien M, Paz Ares L, Peeters S, Pöttgen C, Ramella S, Reck M, Slotman B, Troost EGC, Van Houtte P, Westeel V, Widder J, Mornex F, De Ruysscher D
- Issue date: 2019 Apr
- Does surgically resected small-cell lung cancer without lymph node involvement benefit from prophylactic cranial irradiation?
- Authors: Lou Y, Zhong R, Xu J, Qiao R, Teng J, Zhang Y, Zhang X, Chu T, Zhong H, Han B
- Issue date: 2020 May
- Consolidative thoracic radiotherapy in stage IV small cell lung cancer: Selection of patients amongst European IASLC and ESTRO experts.
- Authors: Putora PM, Glatzer M, De Ruysscher D, Faivre-Finn C, Belderbos J, Besse B, Blackhall F, Califano R, Cappuzzo F, de Marinis F, Dziadiuszko R, Felip E, Früh M, Garrido P, Le Pechoux C, McDonald F, Nestle U, Novello S, Brien MO, Paz Ares L, Peeters S, Pöttgen C, Ramella S, Reck M, Troost EGC, Van Houtte P, Westeel V, Widder J, Mornex F, Slotman BJ
- Issue date: 2019 Jun
- Prophylactic cranial irradiation in patients with resected small-cell lung cancer: A systematic review and meta-analysis.
- Authors: Peng H, Hao J, Dong B, Chen M, Li Z, Chen C, Liu L
- Issue date: 2024 Nov
- Prophylactic cranial irradiation in resected early stage small cell lung cancer: an updated systematic review and meta-analysis.
- Authors: Yuan Z, Tao D, Yang D, Jiang Y, Munai E, Zeng S, Zhou Z, Zhou W, Wu Y
- Issue date: 2025 May 20