A new method to reconstruct in 3D the emission position of the prompt gamma rays following proton beam irradiation
dc.contributor.author | Panaino, Costanza MV | |
dc.contributor.author | Mackay, Ranald I | |
dc.contributor.author | Kirkby, Karen J | |
dc.contributor.author | Taylor, Michael J | |
dc.date.accessioned | 2020-01-29T15:17:48Z | |
dc.date.available | 2020-01-29T15:17:48Z | |
dc.date.issued | 2019 | en |
dc.identifier.citation | Panaino CMV, Mackay RI, Kirkby KJ, Taylor MJ. A New Method to Reconstruct in 3D the Emission Position of the Prompt Gamma Rays following Proton Beam Irradiation. Sci Rep. 2019;9(1):18820. | en |
dc.identifier.pmid | 31827167 | en |
dc.identifier.doi | 10.1038/s41598-019-55349-7 | en |
dc.identifier.uri | http://hdl.handle.net/10541/622665 | |
dc.description.abstract | A new technique for range verification in proton beam therapy has been developed. It is based on the detection of the prompt ? rays that are emitted naturally during the delivery of the treatment. A spectrometer comprising 16 LaBr3(Ce) detectors in a symmetrical configuration is employed to record the prompt ? rays emitted along the proton path. An algorithm has been developed that takes as inputs the LaBr3(Ce) detector signals and reconstructs the maximum ?-ray intensity peak position, in full 3 dimensions. For a spectrometer radius of 8?cm, which could accommodate a paediatric head and neck case, the prompt ?-ray origin can be determined from the width of the detected peak with a ? of 4.17?mm for a 180?MeV proton beam impinging a water phantom. For spectrometer radii of 15 and 25?cm to accommodate larger volumes this value increases to 5.65 and 6.36?mm. For a 8?cm radius, with a 5 and 10?mm undershoot, the ? is 4.31 and 5.47?mm. These uncertainties are comparable to the range uncertainties incorporated in treatment planning. This work represents the first step towards a new accurate, real-time, 3D range verification device for spot-scanning proton beam therapy. | en |
dc.language.iso | en | en |
dc.relation.url | https://dx.doi.org/10.1038/s41598-019-55349-7 | en |
dc.title | A new method to reconstruct in 3D the emission position of the prompt gamma rays following proton beam irradiation | en |
dc.type | Article | en |
dc.contributor.department | Division of Cancer Sciences, University of Manchester, M13 9PL | en |
dc.identifier.journal | Scientific reports | en |
dc.description.note | en] | |
refterms.dateFOA | 2020-02-03T15:08:20Z |