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    Magnetic resonance-guided radiation therapy: A review

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    Authors
    Chin, Stephen
    Eccles, Cynthia L
    McWilliam, Alan
    Chuter, Robert
    Walker, Emma
    Whitehurst, Philip
    Berresford, Joe
    van Herk, Marcel
    Hoskin, Peter J
    Choudhury, Ananya
    Affiliation
    Department of Clinical Oncology, The Christie NHS Foundation Trust, Manchester, UK
    Issue Date
    2019
    
    Metadata
    Show full item record
    Abstract
    Magnetic resonance-guided radiation therapy (MRgRT) is a promising approach to improving clinical outcomes for patients treated with radiation therapy. The roles of image guidance, adaptive planning and magnetic resonance imaging in radiation therapy have been increasing over the last two decades. Technical advances have led to the feasible combination of magnetic resonance imaging and radiation therapy technologies, leading to improved soft-tissue visualisation, assessment of inter- and intrafraction motion, motion management, online adaptive radiation therapy and the incorporation of functional information into treatment. MRgRT can potentially transform radiation oncology by improving tumour control and quality of life after radiation therapy and increasing convenience of treatment by shortening treatment courses for patients. Multiple groups have developed clinical implementations of MRgRT predominantly in the abdomen and pelvis, with patients having been treated since 2014. While studies of MRgRT have primarily been dosimetric so far, an increasing number of trials are underway examining the potential clinical benefits of MRgRT, with coordinated efforts to rigorously evaluate the benefits of the promising technology. This review discusses the current implementations, studies, potential benefits and challenges of MRgRT.
    Citation
    Chin S, Eccles CL, McWilliam A, Chuter R, Walker E, Whitehurst P, et al. Magnetic resonance-guided radiation therapy: A review. J Med Imaging Radiat Oncol. 2019.
    Journal
    Journal of Medical Imaging and Radiation Oncology
    URI
    http://hdl.handle.net/10541/622565
    DOI
    10.1111/1754-9485.12968
    PubMed ID
    31646742
    Additional Links
    https://dx.doi.org/10.1111/1754-9485.12968
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1111/1754-9485.12968
    Scopus Count
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