Authors
Chin, StephenEccles, Cynthia L
McWilliam, Alan
Chuter, Robert
Walker, Emma
Whitehurst, Philip
Berresford, Joe
van Herk, Marcel
Hoskin, Peter J
Choudhury, Ananya
Affiliation
Department of Clinical Oncology, The Christie NHS Foundation Trust, Manchester, UKIssue Date
2019
Metadata
Show full item recordAbstract
Magnetic resonance-guided radiation therapy (MRgRT) is a promising approach to improving clinical outcomes for patients treated with radiation therapy. The roles of image guidance, adaptive planning and magnetic resonance imaging in radiation therapy have been increasing over the last two decades. Technical advances have led to the feasible combination of magnetic resonance imaging and radiation therapy technologies, leading to improved soft-tissue visualisation, assessment of inter- and intrafraction motion, motion management, online adaptive radiation therapy and the incorporation of functional information into treatment. MRgRT can potentially transform radiation oncology by improving tumour control and quality of life after radiation therapy and increasing convenience of treatment by shortening treatment courses for patients. Multiple groups have developed clinical implementations of MRgRT predominantly in the abdomen and pelvis, with patients having been treated since 2014. While studies of MRgRT have primarily been dosimetric so far, an increasing number of trials are underway examining the potential clinical benefits of MRgRT, with coordinated efforts to rigorously evaluate the benefits of the promising technology. This review discusses the current implementations, studies, potential benefits and challenges of MRgRT.Citation
Chin S, Eccles CL, McWilliam A, Chuter R, Walker E, Whitehurst P, et al. Magnetic resonance-guided radiation therapy: A review. J Med Imaging Radiat Oncol. 2019.Journal
Journal of Medical Imaging and Radiation OncologyDOI
10.1111/1754-9485.12968PubMed ID
31646742Additional Links
https://dx.doi.org/10.1111/1754-9485.12968Type
ArticleLanguage
enae974a485f413a2113503eed53cd6c53
10.1111/1754-9485.12968
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