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dc.contributor.authorMevel, R
dc.contributor.authorDraper, JE
dc.contributor.authorLie-A-Ling, Michael
dc.contributor.authorKouskoff, Valerie
dc.contributor.authorLacaud, Georges
dc.date.accessioned2019-10-07T15:16:44Z
dc.date.available2019-10-07T15:16:44Z
dc.date.issued2019en
dc.identifier.citationMevel R, Draper JE, Lie ALM, Kouskoff V, Lacaud G. RUNX transcription factors: orchestrators of development. Development. 2019 Sep 5;146(17).en
dc.identifier.pmid31488508en
dc.identifier.doi10.1242/dev.148296en
dc.identifier.urihttp://hdl.handle.net/10541/622214
dc.description.abstractRUNX transcription factors orchestrate many different aspects of biology, including basic cellular and developmental processes, stem cell biology and tumorigenesis. In this Primer, we introduce the molecular hallmarks of the three mammalian RUNX genes, RUNX1, RUNX2 and RUNX3, and discuss the regulation of their activities and their mechanisms of action. We then review their crucial roles in the specification and maintenance of a wide array of tissues during embryonic development and adult homeostasis.en
dc.language.isoenen
dc.relation.urlhttps://dx.doi.org/10.1242/dev.148296en
dc.titleRUNX transcription factors: orchestrators of developmenten
dc.typeArticleen
dc.contributor.departmentCancer Research UK Stem Cell Biology Group, Cancer Research UK Manchester Institute, The University of Manchester, Alderley Park, Alderley Edge, Macclesfield SK10 4TG,en
dc.identifier.journalDevelopmenten
dc.description.noteen]
refterms.dateFOA2019-10-27T19:12:16Z


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