Activity measurements and determination of nuclear decay data of (166)Ho in the MRTDosimetry project
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Authors
Bobin, CBouchard, J
Chiste, V
Collins, SM
Dryak, P
Fenwick, A
Keightley, J
Lepy, MC
Lourenco, V
Robinson, Andrew P
Sochorova, J
Solc, J
Thiam, C
Affiliation
CEA, LIST, Laboratoire National Henri Becquerel, (LNE-LNHB), 91191, Gif-sur-Yvette Cedex, FranceIssue Date
2019
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Holmium-166 is a high-energy ?--emitter radionuclide (~ 1.8?MeV) with a short half-life (~26.8h) that offers great potential as an alternative to 90Y for the treatment of liver cancer based on radioembolization. The possibility of quantitative Single Photon Emission Computed Tomography (SPECT) imaging of the main ?-ray emission at 80.6?keV, in addition to strong paramagnetic properties suitable for Magnetic Resonance Imaging (MRI), complement this therapeutic potential. The present paper describes the measurements carried out in three European radionuclide metrology laboratories for primary standardization of 166Ho and new determinations of X- and ?-ray photon-emission intensities in the framework of the European EMPIR project MRTDosimetry. New half-life measurements were also performed.Citation
Bobin C, Bouchard J, Chiste V, Collins SM, Dryak P, Fenwick A, et al. Activity measurements and determination of nuclear decay data of (166)Ho in the MRTDosimetry project. Appl Radiat and Isot. 2019 Jul 29;153:108826.Journal
Applied Radiation and IsotopesDOI
10.1016/j.apradiso.2019.108826PubMed ID
31525708Additional Links
https://dx.doi.org/10.1016/j.apradiso.2019.108826Type
ArticleLanguage
enae974a485f413a2113503eed53cd6c53
10.1016/j.apradiso.2019.108826