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    Activity measurements and determination of nuclear decay data of (166)Ho in the MRTDosimetry project

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    Authors
    Bobin, C
    Bouchard, J
    Chiste, V
    Collins, SM
    Dryak, P
    Fenwick, A
    Keightley, J
    Lepy, MC
    Lourenco, V
    Robinson, Andrew P
    Sochorova, J
    Solc, J
    Thiam, C
    Show allShow less
    Affiliation
    CEA, LIST, Laboratoire National Henri Becquerel, (LNE-LNHB), 91191, Gif-sur-Yvette Cedex, France
    Issue Date
    2019
    
    Metadata
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    Abstract
    Holmium-166 is a high-energy ?--emitter radionuclide (~ 1.8?MeV) with a short half-life (~26.8h) that offers great potential as an alternative to 90Y for the treatment of liver cancer based on radioembolization. The possibility of quantitative Single Photon Emission Computed Tomography (SPECT) imaging of the main ?-ray emission at 80.6?keV, in addition to strong paramagnetic properties suitable for Magnetic Resonance Imaging (MRI), complement this therapeutic potential. The present paper describes the measurements carried out in three European radionuclide metrology laboratories for primary standardization of 166Ho and new determinations of X- and ?-ray photon-emission intensities in the framework of the European EMPIR project MRTDosimetry. New half-life measurements were also performed.
    Citation
    Bobin C, Bouchard J, Chiste V, Collins SM, Dryak P, Fenwick A, et al. Activity measurements and determination of nuclear decay data of (166)Ho in the MRTDosimetry project. Appl Radiat and Isot. 2019 Jul 29;153:108826.
    Journal
    Applied Radiation and Isotopes
    URI
    http://hdl.handle.net/10541/622174
    DOI
    10.1016/j.apradiso.2019.108826
    PubMed ID
    31525708
    Additional Links
    https://dx.doi.org/10.1016/j.apradiso.2019.108826
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.apradiso.2019.108826
    Scopus Count
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    All Christie Publications

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