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    PARG inhibitors exhibit synthetic lethality with XRCC1 deficiency and a cellular mechanism of action that is distinct from PARP inhibition

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    Authors
    Martin, Leenus
    Cheng, Tzuling
    James, Dominic I
    Begum, Habiba
    Smith, Kate M
    Jordan, Allan M
    Waddell, Ian D
    Vaidya, Kedar
    Fischer, Marcus
    Yao, Bing
    Drummond, Jason
    Cleary, Leah
    Martinez, Ruben
    Sutton, James
    Ravindran, Nandini
    Joseph, James
    Venetsanakos, Eleni
    Dillon, Michael
    Hager, Jeffrey H
    Belmont, Lisa D
    Show allShow less
    Affiliation
    Ideaya Biosciences, Inc., South San Francisco, CA
    Issue Date
    2018
    
    Metadata
    Show full item record
    Citation
    Martin L, Cheng T, James DI, Begum H, Smith KM, Jordan A, et al. Abstract 1943: PARG inhibitors exhibit synthetic lethality with XRCC1 deficiency and a cellular mechanism of action that is distinct from PARP inhibition. Cancer Res. 2018;78(13):1943.
    Journal
    Cancer Research
    URI
    http://hdl.handle.net/10541/621979
    DOI
    10.1158/1538-7445.AM2018-1943
    Additional Links
    https://dx.doi.org/10.1158/1538-7445.AM2018-1943
    Type
    Meetings and Proceedings
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1158/1538-7445.AM2018-1943
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

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