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    Management of patients with high-risk and advanced prostate cancer in the Middle East: resource-stratified consensus recommendations

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    Authors
    Mukherji, D
    Youssef, B
    Dagher, C
    El-Hajj, A
    Nasr, R
    Geara, F
    Rabah, D
    Al, DS
    Said, R
    Ashou, R
    Wazzan, W
    Jabbour, M
    Farha, G
    Al Hamdani, N
    Al Hallaq, Y
    Ghazal, H
    Dbouk, H
    Bachir, B
    El Khoury, C
    Sakr, G
    Hussain, HK
    Sayyid, K
    Ibrahim, K
    Haidar, M
    Zouain, N
    Bitar, N
    Alameh, W
    Abbas, F
    Faddoul, S
    Nemer, E
    Assaf, G
    Farhat, F
    Bulbul, M
    Temraz, S
    Shamseddine, A
    Gillessen, Silke
    Omlin, A
    Khauli, R
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    Affiliation
    Division of Hematology/Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Riad El Solh, 1107 2020, Beirut, Lebanon.
    Issue Date
    2019
    
    Metadata
    Show full item record
    Abstract
    PURPOSE: Prostate cancer care in the Middle East is highly variable and access to specialist multidisciplinary management is limited. Academic tertiary referral centers offer cutting-edge diagnosis and treatment; however, in many parts of the region, patients are managed by non-specialists with limited resources. Due to many factors including lack of awareness and lack of prostate-specific antigen (PSA) screening, a high percentage of men present with locally advanced and metastatic prostate cancer at diagnosis. The aim of these recommendations is to assist clinicians in managing patients with different levels of access to diagnostic and treatment modalities. METHODS: The first Advanced Prostate Cancer Consensus Conference (APCCC) satellite meeting for the Middle East was held in Beirut, Lebanon, November 2017. During this meeting a consortium of urologists, medical oncologists, radiation oncologist and imaging specialists practicing in Lebanon, Syria, Iraq, Kuwait and Saudi Arabia voted on a selection of consensus questions. An additional workshop to formulate resource-stratified consensus recommendations was held in March 2019. RESULTS: Variations in practice based on available resources have been proposed to form resource-stratified recommendations for imaging at diagnosis, initial management of localized prostate cancer requiring therapy, treatment of castration-sensitive/naive advanced prostate cancer and treatment of castration-resistant prostate cancer. CONCLUSION: This is the first regional consensus on prostate cancer management from the Middle East. The following recommendations will be useful to urologists and oncologists practicing in all areas with limited access to specialist multi-disciplinary teams, diagnostic modalities and treatment resources.
    Citation
    Mukherji D, Youssef B, Dagher C, El-Hajj A, Nasr R, Geara F, et al. Management of patients with high-risk and advanced prostate cancer in the Middle East: resource-stratified consensus recommendations. World J Urol. 2019 Jul 11.
    Journal
    World Journal of Urology
    URI
    http://hdl.handle.net/10541/621970
    DOI
    10.1007/s00345-019-02872-x
    PubMed ID
    31297628
    Additional Links
    https://dx.doi.org/10.1007/s00345-019-02872-x
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1007/s00345-019-02872-x
    Scopus Count
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