• Login
    View Item 
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ChristieCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjects

    My Account

    LoginRegister

    Local Links

    The Christie WebsiteChristie Library and Knowledge Service

    Statistics

    Display statistics

    Sensitivity to change of the EORTC quality of life module measuring cancer related fatigue (EORTC QlQ-Fa12): results from the international psychometric validation

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Weis, J
    Wirtz, M
    Tomaszewski, K
    Hammerlid, E
    Arraras, J
    Conroy, T
    Lanceley, A
    Schmidt, H
    Singer, S
    Pinto, M
    Alm El-Din, M
    Compter, I
    Holzner, B
    Hofmeister, D
    Chie, W
    Harle, Amelie S
    Flechtner, H
    Bottomley, A
    Show allShow less
    Affiliation
    University Clinic Center Freiburg, Comprehensive Cancer Center, Germany
    Issue Date
    2019
    
    Metadata
    Show full item record
    Abstract
    OBJECTIVE: The European Organisation for Research and Treatment of Cancer Quality of Life Group (EORTC QLG) has developed a multidimensional instrument measuring cancer-related fatigue, the EORTC QLQ-FA12. The analysis of sensitivity to change is an essential part of psychometric validation. With this study, we investigated the EORTC QLQ-FA12's sensitivity to change. METHODS: The methodology follows the EORTC guidelines of EORTC QLG for phase IV validation of modules. We included cancer patients undergoing curative and palliative treatment at t1 and followed them up prospectively over the course of their treatment (t2) and 4 weeks after completion of treatment (t3). Data were collected prospectively at 17 sites in 11 countries. Sensitivity to change was investigated using analysis of variance. RESULTS: A total sample of 533 patients was enrolled with various tumour types, different stages of cancer, and receiving either curative treatment (n=311) or palliative treatment (n=222). Over time all fatigue scores were significantly higher in the palliative treatment group compared with the curative group (p < .001). Physical fatigue increased with medium effect size over the course of treatment in the curative group (standardized response mean [SRM] (t1,t2) = 0.44]. After treatment physical [SRM (t2,t3) = 0.39], emotional [SRM (t2,t3)= 0.28] and cognitive fatigue (SRM [t2,t3] = 0.22) declined significantly in the curative group. In the palliative group, emotional (SRM [t2,t3] = 0.18) as well as cognitive [SRM [t2,t3] = 0.26) fatigue increases significantly. CONCLUSIONS: The EORTC-QLQ-FA12 proved to identify clinically significant changes in fatigue in the course of curative and palliative cancer treatment.
    Citation
    Weis J, Wirtz MA, Tomaszewski KA, Hammerlid E, Arraras JI, Conroy T, et al. Sensitivity to change of the EORTC quality of life module measuring cancer related fatigue (EORTC QlQ-Fa12): results from the international psychometric validation. Psychooncology. 2019.
    Journal
    Psycho-oncology
    URI
    http://hdl.handle.net/10541/621929
    DOI
    10.1002/pon.5151
    PubMed ID
    31225669
    Additional Links
    https://dx.doi.org/10.1002/pon.5151
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1002/pon.5151
    Scopus Count
    Collections
    All Christie Publications

    entitlement

    Related articles

    • International Psychometric Validation of an EORTC Quality of Life Module Measuring Cancer Related Fatigue (EORTC QLQ-FA12).
    • Authors: Weis J, Tomaszewski KA, Hammerlid E, Ignacio Arraras J, Conroy T, Lanceley A, Schmidt H, Wirtz M, Singer S, Pinto M, Alm El-Din M, Compter I, Holzner B, Hofmeister D, Chie WC, Czeladzki M, Harle A, Jones L, Ritter S, Flechtner HH, Bottomley A, EORTC Quality of Life Group.
    • Issue date: 2017 May 1
    • Psychometric Properties of the Fatigue Questionnaire EORTC QLQ-FA12 in a Sample of Female Cancer Patients.
    • Authors: Kecke S, Ernst J, Einenkel J, Singer S, Hinz A
    • Issue date: 2017 Dec
    • Psychometric properties of the fatigue questionnaire EORTC QLQ-FA12 and proposal of a cut-off value for young adults with cancer.
    • Authors: Friedrich M, Nowe E, Hofmeister D, Kuhnt S, Leuteritz K, Sender A, Stöbel-Richter Y, Geue K
    • Issue date: 2018 Jun 15
    • Development of an EORTC quality of life phase III module measuring cancer-related fatigue (EORTC QLQ-FA13).
    • Authors: Weis J, Arraras JI, Conroy T, Efficace F, Fleissner C, Görög A, Hammerlid E, Holzner B, Jones L, Lanceley A, Singer S, Wirtz M, Flechtner H, Bottomley A
    • Issue date: 2013 May
    • Fatigue in the general population: German normative values of the EORTC QLQ-FA12.
    • Authors: Hinz A, Weis J, Brähler E, Mehnert A
    • Issue date: 2018 Oct
    DSpace software (copyright © 2002 - 2021)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.