Green, Adele C
AffiliationCancer Control Group, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia
MetadataShow full item record
AbstractOBJECTIVES: Occupational exposure to cosmic and ultraviolet radiation may increase airline pilots' risk of cutaneous melanoma. Meta-analyses of available data show a higher than average incidence of melanoma in airline pilots, but the most recent systematic review revealed that few contemporary data are available. Moreover, all relevant studies have been conducted in Northern Hemisphere populations. We therefore aimed to examine if Australian commercial pilots have a raised incidence of melanoma compared with the general population. METHODS: We examined all melanoma histologically diagnosed among Australian-licensed commercial pilots in the period 2011-2016 by manually reviewing de-identified data in the medical records system of the Australian Civil Aviation Safety Authority. We estimated age-specific incidence rates and compared these with corresponding population rates using standardised incidence ratios (SIRs) as measures of relative risk. Expected numbers were calculated by multiplying age- and calendar period-specific person-years (PYs) with corresponding rates from the entire Australian population; 95% CI were calculated assuming a Poisson distribution of the observed cases. RESULTS: In this cohort of Australian-licensed commercial pilots observed for 91 370 PYs, 114 developed a melanoma (51 invasive, 63 in situ). More than 50% of melanomas occurred on the trunk, and the predominant subtype was superficial spreading melanoma. The SIR for invasive melanoma was 1.20 (95% CI 0.89 to 1.55) and for melanoma in situ, 1.39 (95% CI 1.08 to 1.78). CONCLUSION: Australian-licensed commercial pilots have a modestly raised risk of in situ melanoma but no elevation of invasive melanoma compared with the general population.
CitationOlsen CM, Miura K, Dusingize JC, Hosegood I, Brown R, Drane M, et al. Melanoma incidence in Australian commercial pilots, 2011-2016. Occup Environ Med. 2019 May 21.
JournalOccupational and Environmental Medicine
- The risk of melanoma in airline pilots and cabin crew: a meta-analysis.
- Authors: Sanlorenzo M, Wehner MR, Linos E, Kornak J, Kainz W, Posch C, Vujic I, Johnston K, Gho D, Monico G, McGrath JT, Osella-Abate S, Quaglino P, Cleaver JE, Ortiz-Urda S
- Issue date: 2015 Jan
- Do airline pilots and cabin crew have raised risks of melanoma and other skin cancers? Systematic review and meta-analysis.
- Authors: Miura K, Olsen CM, Rea S, Marsden J, Green AC
- Issue date: 2019 Jul
- Incidence of cancer among licenced commercial pilots flying North Atlantic routes.
- Authors: Gudmundsdottir EM, Hrafnkelsson J, Rafnsson V
- Issue date: 2017 Aug 16
- Incidence of cancer among commercial airline pilots.
- Authors: Rafnsson V, Hrafnkelsson J, Tulinius H
- Issue date: 2000 Mar
- Cancer incidence among Norwegian airline pilots.
- Authors: Haldorsen T, Reitan JB, Tveten U
- Issue date: 2000 Apr