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    Intravenous versus subcutaneous trastuzumab: an economic and patient perspective

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    Authors
    Mitchell, Helen
    Morrissey, Diane
    Affiliation
    The Christie NHS Foundation Trust, ManchesterBreast Care Nurse, The Christie NHS Foundation Trust, Manchester
    Issue Date
    2019
    
    Metadata
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    Abstract
    Since 2005, when the first patients outside of a clinical trial were treated with trastuzumab at The Christie NHS Foundation Trust, a nurse-led service has been developed to facilitate and support a safe treatment pathway for patients. There have been significant developments in the number of patients treated, the mode of administration of the drug and patient choice regarding the location of treatment delivery. This article focuses on the change from intravenous to subcutaneous administration, considering patient experience and choice, particularly in light of the advent of biosimilar drugs, which will necessitate a return to the intravenous route. The relative costs of intravenous and subcutaneous administration are illustrated and the results of a patient survey presented, indicating a strong preference for subcutaneous trastuzumab.
    Citation
    Mitchell H, Morrissey D. Intravenous versus subcutaneous trastuzumab: an economic and patient perspective. Br J Nurs. 2019;28(10):S15-S20.
    Journal
    British Journal of Nursing
    URI
    http://hdl.handle.net/10541/621892
    DOI
    10.12968/bjon.2019.28.10.S15
    PubMed ID
    31116603
    Additional Links
    https://dx.doi.org/10.12968/bjon.2019.28.10.S15
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.12968/bjon.2019.28.10.S15
    Scopus Count
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