RAPPER - A success story for collaborative translational radiotherapy research
Affiliation#Division of Cancer Sciences, University of Manchester, Manchester Cancer Research Centre, Manchester Academic Health Science Centre, Manchester, UK
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AbstractRAPPER (Radiogenomics: Assessment of Polymorphisms for Predicting the Effects of Radiotherapy) is a success story for national collaborative translational science. The study was established with the aim of identifying genetic variants associated with a patient’s risk of developing radiotherapy side-effects that could be combined in a clinical test incorporating non-genetic risk factors to individualise treatment . Underpinned by hypothesis-driven science, RAPPER collects blood to extract germline DNA from patients with high-quality clinical outcome data e collected mainly in national trials led by members of the UK clinical oncology community. It is an effort that we, as a community, should be very proud of. This editorial provides an update on the status of RAPPER and its future ambitions.
CitationBurnet NG, Barnett GC, Summersgill HR, Dunning AM, West CML. RAPPER - A success story for collaborative translational radiotherapy research. Clin Oncol. 2019;31(7):416-9.