Radiotherapy in the control of bleeding from primary and secondary lung tumours
AffiliationClinical Research fellow, Department of Radiotherapy, The Christie NHS Foundation Trust, Manchester M20 4BX
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AbstractThis literature review clarifies the role of radiotherapy in the management of low-volume haemoptysis. Embase and Medline were interrogated, and PRISMA guidelines were then used to select relevant articles. Seventy-eight articles were considered relevant and manually reviewed. The evidence suggests that external beam radiotherapy is more effective than endobronchial brachytherapy at controlling low-volume haemoptysis. There is no evidence to recommend a combination of the two techniques. Different doses and fractionations appear equally effective, with a potential survival advantage of higher dose regimens for fitter patients. Palliative radiotherapy is effective at controlling low-volume haemoptysis. External beam radiotherapy is the first-line treatment, with endobronchial brachytherapy recommended following external beam radiotherapy failure. Choice of dose and fractionation should take into account the patient's performance status.
CitationGaito S, Hughes C, Woolf D, Radhakrishna G. Radiotherapy in the control of bleeding from primary and secondary lung tumours. Br J Hosp Med (Lond). 2019 Apr 2;80(4):211-5.
JournalBritish Journal of Hospital Medicine
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