• Login
    View Item 
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ChristieCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjects

    My Account

    LoginRegister

    Local Links

    The Christie WebsiteChristie Library and Knowledge Service

    Statistics

    Display statistics

    The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    s41436-019-0489-y.pdf
    Size:
    456.3Kb
    Format:
    PDF
    Description:
    Open Access, Full Text Article
    Download
    Authors
    Crosbie, Emma J
    Ryan, N
    Arends, M
    Bosse, T
    Burn, J
    Cornes, J
    Crawford, R
    Eccles, D
    Frayling, I
    Ghaem-Maghami, S
    Hampel, H
    Kauff, N
    Kitchener, H
    Kitson, S
    Manchanda, R
    McMahon, R
    Monahan, K
    Menon, U
    Moller, P
    Moslein, G
    Rosenthal, A
    Sasieni, P
    Seif, M
    Singh, N
    Skarrott, P
    Snowsill, T
    Steele, R
    Tischkowitz, M
    Evans, D Gareth R
    Show allShow less
    Affiliation
    Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, St Mary's Hospital, Manchester, UK
    Issue Date
    2019
    
    Metadata
    Show full item record
    Abstract
    PURPOSE: There are no internationally agreed upon clinical guidelines as to which women with gynecological cancer would benefit from Lynch syndrome screening or how best to manage the risk of gynecological cancer in women with Lynch syndrome. The Manchester International Consensus Group was convened in April 2017 to address this unmet need. The aim of the Group was to develop clear and comprehensive clinical guidance regarding the management of the gynecological sequelae of Lynch syndrome based on existing evidence and expert opinion from medical professionals and patients. METHODS: Stakeholders from Europe and North America worked together over a two-day workshop to achieve consensus on best practice. RESULTS: Guidance was developed in four key areas: (1) whether women with gynecological cancer should be screened for Lynch syndrome and (2) how this should be done, (3) whether there was a role for gynecological surveillance in women at risk of Lynch syndrome, and (4) what preventive measures should be recommended for women with Lynch syndrome to reduce their risk of gynecological cancer. CONCLUSION: This document provides comprehensive clinical guidance that can be referenced by both patients and clinicians so that women with Lynch syndrome can expect and receive appropriate standards of care.
    Citation
    Crosbie EJ, Ryan NAJ, Arends MJ, Bosse T, Burn J, Cornes JM, et al. The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome. Genet Med. 2019.
    Journal
    Genetics in Medicine
    URI
    http://hdl.handle.net/10541/621749
    DOI
    10.1038/s41436-019-0489-y
    PubMed ID
    30918358
    Additional Links
    https://dx.doi.org/10.1038/s41436-019-0489-y
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1038/s41436-019-0489-y
    Scopus Count
    Collections
    All Christie Publications

    entitlement

    Related articles

    • The gynecological surveillance of women with Lynch syndrome in Sweden.
    • Authors: Tzortzatos G, Andersson E, Soller M, Askmalm MS, Zagoras T, Georgii-Hemming P, Lindblom A, Tham E, Mints M
    • Issue date: 2015 Sep
    • The prevalence of Lynch syndrome in women with endometrial cancer: a systematic review protocol.
    • Authors: Ryan NAJ, Blake D, Cabrera-Dandy M, Glaire MA, Evans DG, Crosbie EJ
    • Issue date: 2018 Aug 16
    • Endometrial and ovarian cancer in women with Lynch syndrome: update in screening and prevention.
    • Authors: Lu KH, Daniels M
    • Issue date: 2013 Jun
    • European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender.
    • Authors: Seppälä TT, Latchford A, Negoi I, Sampaio Soares A, Jimenez-Rodriguez R, Sánchez-Guillén L, Evans DG, Ryan N, Crosbie EJ, Dominguez-Valentin M, Burn J, Kloor M, Knebel Doeberitz MV, Duijnhoven FJBV, Quirke P, Sampson JR, Møller P, Möslein G, European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)
    • Issue date: 2021 May 27
    • The results of gynecologic surveillance in families with hereditary nonpolyposis colorectal cancer.
    • Authors: Ketabi Z, Gerdes AM, Mosgaard B, Ladelund S, Bernstein I
    • Issue date: 2014 Jun
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.