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dc.contributor.authorWilson, LF
dc.contributor.authorBaade, PD
dc.contributor.authorGreen, Adèle C
dc.contributor.authorJordan, SJ
dc.contributor.authorKendall, BJ
dc.contributor.authorNeale, RE
dc.contributor.authorOlsen, CM
dc.contributor.authorYoulden, DR
dc.contributor.authorWebb, PM
dc.contributor.authorWhiteman, DC
dc.date.accessioned2019-03-29T14:22:26Z
dc.date.available2019-03-29T14:22:26Z
dc.date.issued2019en
dc.identifier.citationWilson LF, Baade PD, Green AC, Jordan SJ, Kendall BJ, Neale RE, et al. The impact of reducing alcohol consumption in Australia: An estimate of the proportion of potentially avoidable cancers 2013-2037. Int J Cancer. 2019 Feb 12.en
dc.identifier.pmid30748013en
dc.identifier.doi10.1002/ijc.32204en
dc.identifier.urihttp://hdl.handle.net/10541/621642
dc.description.abstractThe International Agency for Research on Cancer first concluded that alcohol causes cancer in humans in 1988. The World Cancer Research Fund has declared that alcohol causes cancer of the oral cavity, pharynx, larynx, oesophagus (squamous cell carcinoma), female breast, colon, rectum, stomach and liver. It recommended that alcohol be avoided altogether to prevent cancer. We aimed to quantify the impact of reducing alcohol consumption on future cancer incidence in Australia. We used PREVENT 3.01 simulation modelling software to estimate the proportion of cancers that could potentially be prevented over a 25-year period under two hypothetical intervention scenarios and two latency periods (20 and 30?years). Under a scenario where alcohol consumption abruptly ceases, we estimated up to 4% of alcohol-related cancers could be avoided over a 25-year period (~49,500 cancers, depending on assumed latency). If the maximum consumption of all Australian adults was ?20?g/day (~two Australian standard drinks), up to 2% of alcohol-related cancers could be avoided (~29,600 cancers). The maximum proportions were higher for men (6% for no alcohol consumption; 5% for ?20?g/day) than women (3%; 1%). The proportion avoidable was highest for oesophageal squamous cell carcinoma (17% no alcohol consumption; 9% ?20?g/day), followed by cancers of the oral cavity (12%; 5%) and pharynx (11%; 5%). The cancer sites with the highest numbers of potentially avoidable cases were colon in men (11,500; 9,900) and breast in women (14,400; 4,100). Successful interventions to reduce alcohol intake could lead to significant reductions in cancer incidence.en
dc.language.isoenen
dc.relation.urlhttps://dx.doi.org/10.1002/ijc.32204en
dc.titleThe impact of reducing alcohol consumption in Australia: an estimate of the proportion of potentially avoidable cancers 2013-2037en
dc.typeArticleen
dc.contributor.departmentPopulation Health Department, QIMR Berghofer Medical Research Institute, Herston, QLD, Australiaen
dc.identifier.journalInternational Journal of Canceren
dc.description.noteen]


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