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    TP53 and prognosis in mCRPC survival: biology or coincidence?

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    Authors
    Rebello, R
    Oing, C
    Gillessen, Silke
    Bristow, Robert G
    Affiliation
    University of Manchester Manchester Cancer Research Centre
    Issue Date
    2018
    
    Metadata
    Show full item record
    Abstract
    Cell-free circulating tumor DNA (ctDNA) or circulating tumor cell (CTC) assays are potentially powerful in the treatment of metastatic castration-resistant prostate cancer (mCRPC). A new study suggests that mutation of TP53 supersedes AR in predicting mCRPC survival. A role for TP53 mutation as a driver for mCRPC remains unexplored.See related article by De Laere et al.
    Citation
    Rebello RJ, Oing C, Gillessen S, Bristow RG. TP53 and prognosis in mCRPC survival: biology or coincidence. Clin Cancer Res. 2019.
    Journal
    Clincal Cancer Research
    URI
    http://hdl.handle.net/10541/621501
    DOI
    10.1158/1078-0432.CCR-18-3401
    PubMed ID
    30610102
    Additional Links
    https://dx.doi.org/10.1158/1078-0432.CCR-18-3401
    Type
    Article
    Language
    en
    ae974a485f413a2113503eed53cd6c53
    10.1158/1078-0432.CCR-18-3401
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