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dc.contributor.authorMercieca, S
dc.contributor.authorBelderbos, JSA
dc.contributor.authorvan BA
dc.contributor.authorDelorme, S
dc.contributor.authorvan Herk, Marcel
dc.date.accessioned2018-12-10T11:48:56Z
dc.date.available2018-12-10T11:48:56Z
dc.date.issued2018en
dc.identifier.citationMercieca S, Belderbos JSA, van Baardwijk A, Delorme S, van Herk M. The impact of training and professional collaboration on the interobserver variation of lung cancer delineations: a multi-institutional study. Acta Oncol. 2018 Oct 30:1-9.en
dc.identifier.pmid30375905en
dc.identifier.doi10.1080/0284186X.2018.1529422en
dc.identifier.urihttp://hdl.handle.net/10541/621419
dc.description.abstractBACKGROUND: To assess the impact of training and interprofessional collaboration on the interobserver variation in the delineation of the lung gross tumor volume (GTVp) and lymph node (GTVln). MATERIAL AND METHODS: Eight target volume delineations courses were organized between 2008 and 2013. Specialists and trainees in radiation oncology were asked to delineate the GTVp and GTVln on four representative CT images of a patient diagnosed with lung cancer individually prior each course (baseline), together as group (interprofessional collaboration) and post-training. The mean delineated volume and local standard deviation (local SD) between the contours for each course group were calculated and compared with the expert delineations. RESULTS: A total 410 delineations were evaluated. The average local SD was lowest for the interprofessional collaboration (GTVp?=?0.194?cm, GTVln?=?0.371?cm) followed by the post-training (GTVp?=?0.244?cm, GTVln?=?0.607?cm) and baseline delineations (GTVp?=?0.274?cm, GTVln: 0.718?cm). The mean delineated volume was smallest for the interprofessional (GTVp?=?4.93?cm3, GTVln?=?4.34?cm3) followed by the post-training (GTVp?=?5.68?cm3, GTVln?=?5.47?cm3) and baseline delineations (GTVp?=?6.65?cm3, GTVln?=?6.93?cm3). All delineations were larger than the expert for both GTVp and GTVln (p?<?.001). CONCLUSION: Our findings indicate that image interpretational differences can lead to large interobserver variation particularly when delineating the GTVln. Interprofessional collaboration was found to have the greatest impact on reducing interobserver variation in the delineation of the GTVln. This highlights the need to develop a clinical workflow so as to ensure that difficult cases are reviewed routinely by a second radiation oncologist or radiologist so as to minimize the risk of geographical tumor miss and unnecessary irradiation to normal tissue.en
dc.language.isoenen
dc.relation.urlhttps://dx.doi.org/10.1080/0284186X.2018.1529422en
dc.titleThe impact of training and professional collaboration on the interobserver variation of lung cancer delineations: a multi-institutional studyen
dc.typeArticleen
dc.contributor.departmentFaculty of Health Science , University of Malta . Msida , Maltaen
dc.identifier.journalActa Oncolen


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