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    Factors affecting local regrowth after watch and wait for patients with a clinical complete response following chemoradiotherapy in rectal cancer (InterCoRe consortium): an individual participant data meta-analysis.

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    Authors
    Chadi, S
    Malcomson, Lee
    Ensor, J
    Riley, R
    Vaccaro, C
    Rossi, G
    Daniels, I
    Smart, N
    Osborne, M
    Beets, G
    Maas, M
    Bitterman, D
    Du, K
    Gollins, S
    Sun Myint, A
    Smith, F
    Saunders, Mark P
    Scott, N
    O'Dwyer, Sarah T
    de Castro Araujo, R
    Valadao, M
    Lopes, A
    Hsiao, C
    Lai, C
    Smith, R
    Paulson, E
    Appelt, A
    Jakobsen, A
    Wexner, S
    Habr-Gama, A
    Sao Julião, G
    Perez, R
    Renehan, Andrew G
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    Affiliation
    Division of Surgical Oncology and General Surgery, Princess Margaret Hospital and University Health Network, University of Toronto, Toronto, ON, Canada
    Issue Date
    2018-10-11
    
    Metadata
    Show full item record
    Abstract
    In patients with rectal cancer who achieve clinical complete response after neoadjuvant chemoradiotherapy, watch and wait is a novel management strategy with potential to avoid major surgery. Study-level meta-analyses have reported wide variation in the proportion of patients with local regrowth. We did an individual participant data meta-analysis to investigate factors affecting occurrence of local regrowth.
    Citation
    Factors affecting local regrowth after watch and wait for patients with a clinical complete response following chemoradiotherapy in rectal cancer (InterCoRe consortium): an individual participant data meta-analysis. 2018 Lancet Gastroenterol Hepatol
    Journal
    The Lancet. Gastroenterology & Hepatology
    URI
    http://hdl.handle.net/10541/621332
    DOI
    10.1016/S2468-1253(18)30301-7
    PubMed ID
    30318451
    Type
    Article
    Language
    en
    ISSN
    2468-1253
    ae974a485f413a2113503eed53cd6c53
    10.1016/S2468-1253(18)30301-7
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