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    Genomic classifier for guiding treatment of intermediate-risk prostate cancers to dose-escalated image-guided radiotherapy without hormone therapy.

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    Authors
    Berlin, A
    Murgic, J
    Hosni, A
    Pintilie, M
    Salcedo, A
    Fraser, M
    Kamel-Reid, S
    Zhang, J
    Wang, Q
    Ch'ng, C
    Deheshi, S
    Davicioni, E
    van der Kwast, T
    Boutros, P
    Bristow, Robert G
    Chua, M
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    Affiliation
    Princess Margaret Cancer Centre, University Health Network, Ontario, Canada
    Issue Date
    2018-08-28
    
    Metadata
    Show full item record
    Abstract
    The NCCN has recently endorsed the stratification of intermediate-risk prostate cancer (IR-PCa) into favorable and unfavourable subgourps, and recommend the addition of androgen deprivation therapy (ADT) to radiotherapy (RT) for unfavorable IR-PCa. Recently, more accurate prognostication was demonstrated by integrating a 22-feature genomic classifier (GC) to the NCCN stratification system. Here, we test the utility of the GC to better identify IR-PCa patients who are sufficiently treated by RT alone.
    Citation
    Genomic classifier for guiding treatment of intermediate-risk prostate cancers to dose-escalated image-guided radiotherapy without hormone therapy. 2018, Int J Radiat Oncol Biol Phys
    Journal
    International Journal of Radiation Oncology, Biology, Physics
    URI
    http://hdl.handle.net/10541/621249
    DOI
    10.1016/j.ijrobp.2018.08.030
    PubMed ID
    30170099
    Type
    Article
    Language
    en
    ISSN
    1879-355X
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.ijrobp.2018.08.030
    Scopus Count
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    All Paterson Institute for Cancer Research

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