Correlation of extent of ALK FISH positivity and crizotinib efficacy in three prospective studies of ALK-positive patients with non-small cell lung cancer.
Authors
Soria, JHo, S
Varella-Garcia, M
Iafrate, A
Solomon, B
Shaw, A
Blackhall, Fiona H
Mok, T
Wu, Y
Pestova, K
Wilner, K
Polli, A
Paolini, J
Lanzalone, S
Green, S
Camidge, D
Affiliation
Department of Medical Oncology, Gustave Roussy Cancer Campus, Villejuif, FranceIssue Date
2018-07-13
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Show full item recordAbstract
In clinical trials of patients with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) treated with crizotinib, evaluation of the relationship between the percentage of ALK-positive cells by fluorescence in situ hybridization (FISH)-particularly near the cutoff defining positive status-and clinical outcomes have been limited by small sample sizes.Citation
Correlation of extent of ALK FISH positivity and crizotinib efficacy in three prospective studies of ALK-positive patients with non-small cell lung cancer. 2018, Ann OncolJournal
Annals of OncologyDOI
10.1093/annonc/mdy242PubMed ID
30010763Type
ArticleLanguage
enISSN
1569-8041ae974a485f413a2113503eed53cd6c53
10.1093/annonc/mdy242
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