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    Inter-comparison of quantitative imaging of lutetium-177 (177Lu) in European hospitals.

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    Authors
    Wevrett, J
    Fenwick, A
    Scuffham, J
    Johansson, L
    Gear, J
    Schlögl, S
    Segbers, M
    Sjögreen-Gleisner, K
    Solný, P
    Lassmann, M
    Tipping, Jill
    Nisbet, A
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    Affiliation
    University of Surrey, Guildford, UK
    Issue Date
    2018-08-02
    
    Metadata
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    Abstract
    This inter-comparison exercise was performed to demonstrate the variability of quantitative SPECT/CT imaging for lutetium-177 (177Lu) in current clinical practice. Our aim was to assess the feasibility of using international inter-comparison exercises as a means to ensure consistency between clinical sites whilst enabling the sites to use their own choice of quantitative imaging protocols, specific to their systems. Dual-compartment concentric spherical sources of accurately known activity concentrations were prepared and sent to seven European clinical sites. The site staff were not aware of the true volumes or activity within the sources-they performed SPECT/CT imaging of the source, positioned within a water-filled phantom, using their own choice of parameters and reported their estimate of the activities within the source.
    Citation
    Inter-comparison of quantitative imaging of lutetium-177 (177Lu) in European hospitals. 2018, 5(1): 17 EJNMMI Phys
    Journal
    EJNMMI Physics
    URI
    http://hdl.handle.net/10541/621206
    DOI
    10.1186/s40658-018-0213-z
    PubMed ID
    30069805
    Type
    Article
    Language
    en
    ISSN
    2197-7364
    ae974a485f413a2113503eed53cd6c53
    10.1186/s40658-018-0213-z
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