Inter-comparison of quantitative imaging of lutetium-177 (177Lu) in European hospitals.
Authors
Wevrett, JFenwick, A
Scuffham, J
Johansson, L
Gear, J
Schlögl, S
Segbers, M
Sjögreen-Gleisner, K
Solný, P
Lassmann, M
Tipping, Jill
Nisbet, A
Affiliation
University of Surrey, Guildford, UKIssue Date
2018-08-02
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This inter-comparison exercise was performed to demonstrate the variability of quantitative SPECT/CT imaging for lutetium-177 (177Lu) in current clinical practice. Our aim was to assess the feasibility of using international inter-comparison exercises as a means to ensure consistency between clinical sites whilst enabling the sites to use their own choice of quantitative imaging protocols, specific to their systems. Dual-compartment concentric spherical sources of accurately known activity concentrations were prepared and sent to seven European clinical sites. The site staff were not aware of the true volumes or activity within the sources-they performed SPECT/CT imaging of the source, positioned within a water-filled phantom, using their own choice of parameters and reported their estimate of the activities within the source.Citation
Inter-comparison of quantitative imaging of lutetium-177 (177Lu) in European hospitals. 2018, 5(1): 17 EJNMMI PhysJournal
EJNMMI PhysicsDOI
10.1186/s40658-018-0213-zPubMed ID
30069805Type
ArticleLanguage
enISSN
2197-7364ae974a485f413a2113503eed53cd6c53
10.1186/s40658-018-0213-z
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