Intracystic interferon-alpha in pediatric craniopharyngioma patients: an international multicenter assessment on behalf of SIOPE and ISPN.

Kilday, John-Paul; Caldarelli, M; Massimi, L; Chen, R; Lee, Y; Liang, M; Parkes, J; Naiker, T; van Veelen, M; Michiels, E; Mallucci, C; Pettorini, B; Meijer, L; Dorfer, C; Czech, T; Diezi, M; Schouten-van Meeteren, A; Holm, S; Gustavsson, B; Benesch, M; Müller, H; Hoffmann, A; Rutkowski, S; Flitsch, J; Escherich, G; Grotzer, M; Spoudeas, H; Azquikina, K; Capra, M; Jiménez-Guerra, R; MacDonald, P; Johnston, D; Dvir, R; Constantini, S; Kuo, M; Yang, S; Bartels, U

Affiliation

Children's Brain Tumour Research Network (CBTRN), Royal Manchester Children's Hospital, Oxford Road, Manchester, England, UK;

Issue Date

2017-10-01

Metadata

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Abstract

Craniopharyngiomas are frequent hypothalamo-pituitary tumors in children, presenting predominantly as cystic lesions. Morbidity from conventional treatment has focused attention on intracystic drug delivery, hypothesized to cause fewer clinical consequences. However, the efficacy of intracystic therapy remains unclear. We report the retrospective experiences of several global centers using intracystic interferon-alpha.

Citation

Intracystic interferon-alpha in pediatric craniopharyngioma patients: an international multicenter assessment on behalf of SIOPE and ISPN. 2017, 19(10): 1398-1407 Neuro-oncology

Journal

Neuro-Oncology

URI

http://hdl.handle.net/10541/621155

DOI

10.1093/neuonc/nox056

PubMed ID

28499018

Type

Article

Language

ISSN

1523-5866

Collections

All Paterson Institute for Cancer Research