Circulating biomarkers during treatment in patients with advanced biliary tract cancer receiving cediranib in the UK ABC-03 trial.
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Authors
Backen, Alison CLopes, A
Wasan, H
Palmer, D
Duggan, M
Cunningham, D
Anthoney, A
Corrie, P
Madhusudan, S
Maraveyas, A
Ross, P
Waters, J
Steward, W
Rees, C
McNamara, Mairéad G
Beare, S
Bridgewater, J
Dive, Caroline
Valle, Juan W
Affiliation
Centre for Cancer Biomarker Sciences, Cancer Research UK Manchester Institute, Manchester, M20 4BX, UKIssue Date
2018-06-21
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Advanced biliary tract cancer (ABC) has a poor prognosis. Cediranib, in addition to cisplatin/gemcitabine [CisGem], improved the response rate, but did not improve the progression-free survival (PFS) in the ABC-03 study. Minimally invasive biomarkers predictive of cediranib benefit may improve patient outcomes.Citation
Circulating biomarkers during treatment in patients with advanced biliary tract cancer receiving cediranib in the UK ABC-03 trial. 2018, Br J CancerJournal
British Journal of CancerDOI
10.1038/s41416-018-0132-8PubMed ID
29925934Type
ArticleLanguage
enISSN
1532-1827ae974a485f413a2113503eed53cd6c53
10.1038/s41416-018-0132-8
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