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    Circulating biomarkers during treatment in patients with advanced biliary tract cancer receiving cediranib in the UK ABC-03 trial.

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    Authors
    Backen, Alison C
    Lopes, A
    Wasan, H
    Palmer, D
    Duggan, M
    Cunningham, D
    Anthoney, A
    Corrie, P
    Madhusudan, S
    Maraveyas, A
    Ross, P
    Waters, J
    Steward, W
    Rees, C
    McNamara, Mairéad G
    Beare, S
    Bridgewater, J
    Dive, Caroline
    Valle, Juan W
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    Affiliation
    Centre for Cancer Biomarker Sciences, Cancer Research UK Manchester Institute, Manchester, M20 4BX, UK
    Issue Date
    2018-06-21
    
    Metadata
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    Abstract
    Advanced biliary tract cancer (ABC) has a poor prognosis. Cediranib, in addition to cisplatin/gemcitabine [CisGem], improved the response rate, but did not improve the progression-free survival (PFS) in the ABC-03 study. Minimally invasive biomarkers predictive of cediranib benefit may improve patient outcomes.
    Citation
    Circulating biomarkers during treatment in patients with advanced biliary tract cancer receiving cediranib in the UK ABC-03 trial. 2018, Br J Cancer
    Journal
    British Journal of Cancer
    URI
    http://hdl.handle.net/10541/621134
    DOI
    10.1038/s41416-018-0132-8
    PubMed ID
    29925934
    Type
    Article
    Language
    en
    ISSN
    1532-1827
    ae974a485f413a2113503eed53cd6c53
    10.1038/s41416-018-0132-8
    Scopus Count
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