• Login
    View Item 
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ChristieCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjectsProfilesView

    My Account

    LoginRegister

    Local Links

    The Christie WebsiteChristie Library and Knowledge Service

    Statistics

    Display statistics

    Biliary tract cancer: implicated immune-mediated pathways and their associated potential targets.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    Submitted 4 April Biliary tract ...
    Size:
    88.00Kb
    Format:
    Microsoft Word 2007
    Description:
    author manuscript
    Download
    Authors
    Tariq, Noor-Ul-Ain
    Vogel, A
    McNamara, Mairéad G
    Valle, Juan W
    Affiliation
    The Christie Hospital NHS Trust, Manchester
    Issue Date
    2018
    
    Metadata
    Show full item record
    Abstract
    There is a well-established link between biliary tract cancers (BTC) and chronic inflammatory conditions such as primary sclerosing cholangitis, chronic cholecystitis, chronic cholelithiasis, liver fluke-associated infestations, and chronic viral hepatic infections. These associated risk factors highlight the potential for development of immune-modulatory agents in this poor-prognostic disease group with limited treatment options. Clinical trials have evaluated the role of immune cells, inflammatory biomarkers, vaccines, cytokines, adoptive cell therapy, and immune checkpoint inhibitors in patients with BTC. Although these have demonstrated the importance of the immune environment in BTC, currently none of the immune-based therapies have been approved for use in this disease group. The role of immunomodulatory agents is a developing field and has yet to find its way 'from bench to bedside' in BTC.
    Citation
    Biliary tract cancer: implicated immune-mediated pathways and their associated potential targets. 2018, 41(5): 298-304 Oncol Res Treat
    Journal
    Oncology Research and Treatment
    URI
    http://hdl.handle.net/10541/621077
    DOI
    10.1159/000488997
    PubMed ID
    29705791
    Type
    Article
    Language
    en
    ISSN
    2296-5262
    ae974a485f413a2113503eed53cd6c53
    10.1159/000488997
    Scopus Count
    Collections
    All Christie Publications

    entitlement

    Related articles

    • Immunotherapy of Hepatocellular Carcinoma.
    • Authors: Heinrich B, Czauderna C, Marquardt JU
    • Issue date: 2018
    • Prognostic significance of tumor immune microenvironment and immunotherapy: Novel insights and future perspectives in gastric cancer.
    • Authors: Lazăr DC, Avram MF, Romoșan I, Cornianu M, Tăban S, Goldiș A
    • Issue date: 2018 Aug 28
    • Immunotherapy as a treatment for biliary tract cancers: A review of approaches with an eye to the future.
    • Authors: Blair AB, Murphy A
    • Issue date: 2018 Jan-Feb
    • Immunotherapeutic Approaches to Biliary Cancer.
    • Authors: Shah UA, Nandikolla AG, Rajdev L
    • Issue date: 2017 Jul
    • Clinical development of immunotherapy for prostate cancer.
    • Authors: Noguchi M, Koga N, Igawa T, Itoh K
    • Issue date: 2017 Sep
    DSpace software (copyright © 2002 - 2025)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.