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    Primary mutational landscape linked with pre-docetaxel lactate dehydrogenase levels predicts docetaxel response in metastatic castrate-resistant prostate cancer.

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    Authors
    Hiew, Kenneth
    Hart, Claire A
    Ali, Adnan
    Elliott, Tony
    Ramani, Vijay A C
    Sangar, Vijay K
    Lau, Maurice W
    Maddineni, Satish B
    Brown, Michael D
    Clarke, Noel W
    Affiliation
    Genito Urinary Cancer Research Group, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine & Health, The University of Manchester, Manchester, UK
    Issue Date
    2018-04-23
    
    Metadata
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    Abstract
    Docetaxel chemotherapy is a standard of care for metastatic castrate-resistant prostate cancer (mCRPC): 40-50% of patients achieve a biochemical response. However, there is a lack of response predictive biomarkers.
    Citation
    Primary mutational landscape linked with pre-docetaxel lactate dehydrogenase levels predicts docetaxel response in metastatic castrate-resistant prostate cancer. 2018, Eur Urol Focus
    Journal
    European Urology Focus
    URI
    http://hdl.handle.net/10541/621073
    DOI
    10.1016/j.euf.2018.04.006
    PubMed ID
    29699892
    Type
    Article
    Language
    en
    ISSN
    2405-4569
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.euf.2018.04.006
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