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    Sex and interleukin-6 are prognostic factors for autoimmune toxicity following treatment with anti-CTLA4 blockade.

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    Authors
    Valpione, Sara
    Pasquali, S
    Campana, L
    Piccin, L
    Mocellin, S
    Pigozzo, J
    Chiarion-Sileni, V
    Affiliation
    CRUK Manchester Institute and The Christie NHS Foundation Trust, The University of Manchester, Manchester, M20 4GJ
    Issue Date
    2018-04-11
    
    Metadata
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    Abstract
    Ipilimumab is a licensed immunotherapy for metastatic melanoma patients and, in the US, as adjuvant treatment for high risk melanoma radically resected. The use of ipilimumab is associated with a typical but unpredictable pattern of side effects. The purpose of this study was to identify clinical features and blood biomarkers capable of predicting ipilimumab related toxicity.
    Citation
    Sex and interleukin-6 are prognostic factors for autoimmune toxicity following treatment with anti-CTLA4 blockade. 2018, 16(1): 94 J Transl Med
    Journal
    Journal of Translational Medicine
    URI
    http://hdl.handle.net/10541/621000
    DOI
    10.1186/s12967-018-1467-x
    PubMed ID
    29642948
    Type
    Article
    Language
    en
    ISSN
    1479-5876
    ae974a485f413a2113503eed53cd6c53
    10.1186/s12967-018-1467-x
    Scopus Count
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