Development of MR quantified pancreatic fat deposition as a cancer risk biomarker.
AffiliationDivision of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, and Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK
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AbstractExcess body adiposity is associated with increased risk of pancreatic cancer, and in animal models excess intra-pancreatic fat is a driver of pancreatic carcinogenesis. Within a programme to evaluate pancreatic fat and PC risk in humans, we assessed whether MR-quantified pancreatic fat fraction (PFF) was 'fit for purpose' as an imaging biomarker.
CitationDevelopment of MR quantified pancreatic fat deposition as a cancer risk biomarker. 2018, Pancreatology
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