Systematic review of outcome measures following chemoradiotherapy for the treatment of anal cancer (CORMAC).
AffiliationDivision of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Vaughan House, Portsmouth Street, Manchester, M13 9GB
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AbstractSix Phase III randomized trials have determined the effectiveness of chemoradiotherapy as primary treatment for anal squamous cell carcinoma (ASCC), but outcomes reported in these trials varied widely, hindering evidence synthesis. To improve reporting in all future trials, we aim to develop a core outcomes set (COS). As the first stage of COS development, we undertook a systematic review to summarize the outcomes reported in studies evaluating chemoradiotherapy for ASCC.
CitationSystematic review of outcome measures following chemoradiotherapy for the treatment of anal cancer (CORMAC). 2018, 20(5): 371-382 Colorectal Dis